用NLP和大模型自动分类与总结临床试验入组条件。

Clinical trials are central to medical progress because they help improve understanding of human health and the healthcare system. They play a key role in discovering new ways to detect, prevent, or treat diseases, and it is essential that clinical trials include participants with appropriate and diverse medical backgrounds. In this paper, we propose a system that leverages Natural Language Processing (NLP) and Large Language Models (LLMs) to automate multi-label clinical text eligibility classification and summarization. The system combines feature extraction methods such as word embeddings (Word2Vec) and named entity recognition to identify relevant medical concepts, along with traditional vectorization techniques such as count vectorization and TF-IDF (Term Frequency-Inverse Document Frequency). We further explore weighted TF-IDF word embeddings that integrate both count-based and embedding-based strengths to capture term importance effectively. Multi-label classification using Random Forest and SVM models is applied to categorize documents based on eligibility criteria. Summarization techniques including TextRank, Luhn, and GPT-3 are evaluated to concisely summarize eligibility requirements. Evaluation with ROUGE scores demonstrates the effectiveness of the proposed methods. This system shows potential for automating clinical trial eligibility assessment using data-driven approaches, thereby improving research efficiency.