用卷积神经网络结合硬件优化,提升口腔癌早期检测准确率
Designing a Convolutional Neural Network for High-Accuracy Oral Cavity Squamous Cell Carcinoma (OCSCC) Detection
- 构建CNN模型并训练4293张图像识别口腔癌
- 分辨率越高预测越准,但收益随像素提升递减
- 配套开发软硬件系统,支持低门槛临床应用
口腔鳞状细胞癌(OCSCC)是头颈部最常见的癌症类型。由于早期症状隐匿、病灶深藏且生长缓慢,常被漏诊,导致可预防的死亡。本文提出一种基于卷积神经网络(CNN)的检测方法,利用其图像分割与核矩阵处理能力实现精准模式识别。在4293张包含良性、恶性肿瘤及阴性样本的图像上训练模型,并使用随机组合的测试集评估其精度、召回率与平均精度均值(mAP)。测试数据按5种常见分辨率进行调整,结果表明图像分辨率提升呈现对数增长的准确率改善,但边际效益递减。同时设计了配套成像采集与处理硬件系统,验证其对预测性能的影响。开发了可视化应用以实现开放访问与测试流程简化。
原文摘要 · Abstract (English)
Oral Cavity Squamous Cell Carcinoma (OCSCC) is the most common type of head and neck cancer. Due to the subtle nature of its early stages, deep and hidden areas of development, and slow growth, OCSCC often goes undetected, leading to preventable deaths. However, properly trained Convolutional Neural Networks (CNNs), with their precise image segmentation techniques and ability to apply kernel matrices to modify the RGB values of images for accurate image pattern recognition, would be an effective means for early detection of OCSCC. Pairing this neural network with image capturing and processing hardware would allow increased efficacy in OCSCC detection. The aim of our project is to develop a Convolutional Neural Network trained to recognize OCSCC, as well as to design a physical hardware system to capture and process detailed images, in order to determine the image quality required for accurate predictions. A CNN was trained on 4293 training images consisting of benign and malignant tumors, as well as negative samples, and was evaluated for its precision, recall, and Mean Average Precision (mAP) in its predictions of OCSCC. A testing dataset of randomly assorted images of cancerous, non-cancerous, and negative images was chosen, and each image was altered to represent 5 common resolutions. This test data set was thoroughly analyzed by the CNN and predictions were scored on the basis of accuracy. The designed enhancement hardware was used to capture detailed images, and its impact was scored. An application was developed to facilitate the testing process and bring open access to the CNN. Images of increasing resolution resulted in higher-accuracy predictions on a logarithmic scale, demonstrating the diminishing returns of higher pixel counts.
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