用物理约束神经场重建超声血流,无需标注数据也能高精度补全和去噪。
Dynamic Reconstruction of Ultrasound-Derived Flow Fields With Physics-Informed Neural Fields
- 引入多尺度傅里叶特征编码的物理信息神经场,从稀疏噪声数据中估计血流。
- 在合成与真实数据上均实现低均方误差,且与参考流场和流量测量一致。
- 首次将该方法用于超声血流重建,适合无辐射成像与心脏疾病诊断场景。
血液流动对疾病敏感,是评估心脏功能的重要依据。尽管超声成像更安全、适合带医疗植入物患者,但其随深度衰减导致图像质量下降。虽然超声粒子图像测速(EchoPIV)已有进展,但受技术局限与血流复杂性影响,速度测量仍具挑战。物理信息机器学习可提升准确性与鲁棒性,尤其在数据噪声大或不完整时表现优异。本文提出一种基于多尺度傅里叶特征编码的物理信息神经场模型,无需真实标注即可从稀疏噪声超声数据中估计血流。实验表明,该模型在合成与真实数据上均表现出稳定的低均方误差,在去噪与补全任务中经参考流场及流量测量验证。尽管物理信息神经场已广泛应用于医学图像重建,其在血流重建中的应用主要集中于流MRI。本工作首次将该方法迁移至超声血流重建,解决特定挑战。
原文摘要 · Abstract (English)
Blood flow is sensitive to disease and provides insight into cardiac function, making flow field analysis valuable for diagnosis. However, while safer than radiation-based imaging and more suitable for patients with medical implants, ultrasound suffers from attenuation with depth, limiting the quality of the image. Despite advances in echocardiographic particle image velocimetry (EchoPIV), accurately measuring blood velocity remains challenging due to the technique's limitations and the complexity of blood flow dynamics. Physics-informed machine learning can enhance accuracy and robustness, particularly in scenarios where noisy or incomplete data challenge purely data-driven approaches. We present a physics-informed neural field model with multi-scale Fourier Feature encoding for estimating blood flow from sparse and noisy ultrasound data without requiring ground truth supervision. We demonstrate that this model achieves consistently low mean squared error in denoising and inpainting both synthetic and real datasets, verified against reference flow fields and ground truth flow rate measurements. While physics-informed neural fields have been widely used to reconstruct medical images, applications to medical flow reconstruction are mostly prominent in Flow MRI. In this work, we adapt methods that have proven effective in other imaging modalities to address the specific challenge of ultrasound-based flow reconstruction.
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