arXiv:2511.02824cs.AI2025-11被引 91

Kosmos是能自主完成科学发现的AI科学家,可连续运行12小时生成高质量科研成果。

Kosmos: An AI Scientist for Autonomous Discovery

  • 构建结构化世界模型,让数据分析与文献检索协同推进
  • 单次运行执行4.2万行代码、阅读1500篇论文,生成79.4%准确的结论
  • 适合需要长期探索的跨领域研究,可替代数月人工工作量

数据驱动的科学发现依赖于文献检索、假说生成与数据分析的迭代循环。尽管已有诸多AI代理尝试自动化科研,但其行动能力受限,难以维持长期一致性。本文提出Kosmos,一种可自主开展数据驱动发现的AI科学家。给定开放目标与数据集后,Kosmos可连续运行长达12小时,执行并行的数据分析、文献检索与假说生成,并将结果整合为科学报告。不同于以往系统,Kosmos通过结构化世界模型实现数据分析代理与文献搜索代理间的信息共享,从而在200次代理推演中保持连贯性,单次运行平均执行42,000行代码,阅读1,500篇论文。其报告中的所有陈述均附有代码或原始文献引用,确保推理可追溯。独立科学家评估显示,报告中79.4%的陈述准确;合作研究人员表示,一次20轮运行相当于节省6个月研究时间。此外,有价值发现数量随运行轮次线性增长(测试至20轮)。我们展示了Kosmos在代谢组学、材料科学、神经科学与统计遗传学领域的七项发现:三项复现了未被Kosmos访问的预印本/未发表成果,四项为原创贡献。

原文摘要 · Abstract (English)

Data-driven scientific discovery requires iterative cycles of literature search, hypothesis generation, and data analysis. Substantial progress has been made towards AI agents that can automate scientific research, but all such agents remain limited in the number of actions they can take before losing coherence, thus limiting the depth of their findings. Here we present Kosmos, an AI scientist that automates data-driven discovery. Given an open-ended objective and a dataset, Kosmos runs for up to 12 hours performing cycles of parallel data analysis, literature search, and hypothesis generation before synthesizing discoveries into scientific reports. Unlike prior systems, Kosmos uses a structured world model to share information between a data analysis agent and a literature search agent. The world model enables Kosmos to coherently pursue the specified objective over 200 agent rollouts, collectively executing an average of 42,000 lines of code and reading 1,500 papers per run. Kosmos cites all statements in its reports with code or primary literature, ensuring its reasoning is traceable. Independent scientists found 79.4% of statements in Kosmos reports to be accurate, and collaborators reported that a single 20-cycle Kosmos run performed the equivalent of 6 months of their own research time on average. Furthermore, collaborators reported that the number of valuable scientific findings generated scales linearly with Kosmos cycles (tested up to 20 cycles). We highlight seven discoveries made by Kosmos that span metabolomics, materials science, neuroscience, and statistical genetics. Three discoveries independently reproduce findings from preprinted or unpublished manuscripts that were not accessed by Kosmos at runtime, while four make novel contributions to the scientific literature.

AI科学家自主发现跨学科科研自动化

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