arXiv:2511.04071eess.IVcs.AI2025-11

用自动配置的深度学习模型精准分割心脏核磁共振中的左心房。

Left Atrial Segmentation with nnU-Net Using MRI

  • 采用自配置的nnU-Net框架,自动优化预处理与网络结构。
  • 平均Dice系数达93.5,分割结果接近专家标注水平。
  • 对不同形状、对比度和图像质量均有良好泛化能力,适合临床应用。

从心脏磁共振中准确分割左心房对指导房颤消融和构建生物物理心脏模型至关重要。手动勾画耗时且依赖观察者,难以用于大规模或时间敏感的临床流程。深度学习方法,尤其是卷积架构,在医学图像分割任务中表现优异。本研究将nnU-Net框架——一种自动、自配置的深度学习分割架构——应用于2013年左心房分割挑战赛数据集。该数据集包含30例带专家标注掩膜的心脏MRI扫描。nnU-Net自动适应数据特征,优化预处理、网络配置与训练流程。通过骰子相似系数(DSC)定量评估性能,并与专家分割结果进行定性比较。所提nnU-Net模型平均获得93.5的骰子分数,表现出与专家标注高度重合的结果,优于以往研究中多种传统分割方法。该网络在左心房形态、对比度和图像质量变化下均展现出强鲁棒性,能准确勾画心房主体及近端肺静脉。

原文摘要 · Abstract (English)

Accurate segmentation of the left atrium (LA) from cardiac MRI is critical for guiding atrial fibrillation (AF) ablation and constructing biophysical cardiac models. Manual delineation is time-consuming, observer-dependent, and impractical for large-scale or time-sensitive clinical workflows. Deep learning methods, particularly convolutional architectures, have recently demonstrated superior performance in medical image segmentation tasks. In this study, we applied the nnU-Net framework, an automated, self-configuring deep learning segmentation architecture, to the Left Atrial Segmentation Challenge 2013 dataset. The dataset consists of thirty MRI scans with corresponding expert-annotated masks. The nnU-Net model automatically adapted its preprocessing, network configuration, and training pipeline to the characteristics of the MRI data. Model performance was quantitatively evaluated using the Dice similarity coefficient (DSC), and qualitative results were compared against expert segmentations. The proposed nnUNet model achieved a mean Dice score of 93.5, demonstrating high overlap with expert annotations and outperforming several traditional segmentation approaches reported in previous studies. The network exhibited robust generalization across variations in left atrial shape, contrast, and image quality, accurately delineating both the atrial body and proximal pulmonary veins.

左心房分割nnU-Net心脏MRI深度学习

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