arXiv:2511.07094eess.IVcs.CV2025-11

让CT重建更懂诊断任务,关键细节不丢失。

Task-Adaptive Low-Dose CT Reconstruction

  • 用预训练诊断模型当约束,指导低剂量重建
  • 肝肿瘤分割Dice达0.707,接近全剂量水平
  • 可插件式接入现有模型,适合临床落地

基于深度学习的低剂量计算机断层扫描(CT)重建方法在峰值信噪比和结构相似性等标准指标上表现优异,但常无法保留诊断所需的关键解剖细节,限制了其临床应用。本文提出一种任务自适应重建框架,通过将冻结的预训练任务网络作为重建损失函数中的正则化项,引导重建过程。与同时优化重建和任务网络的联合训练方法不同,该方法在保持高质量重建的同时提升诊断相关性能。我们在肝脏及肝肿瘤分割任务上验证了该框架,任务自适应模型的Dice分数最高达0.707,接近全剂量扫描的0.874,显著优于联合训练方法(0.331)和传统方法(0.626)。该框架可通过简单修改损失函数集成到任意现有深度学习重建模型中,便于在临床实践中推广。代码已开源。

原文摘要 · Abstract (English)

Deep learning-based low-dose computed tomography reconstruction methods already achieve high performance on standard image quality metrics like peak signal-to-noise ratio and structural similarity index measure. Yet, they frequently fail to preserve the critical anatomical details needed for diagnostic tasks. This fundamental limitation hinders their clinical applicability despite their high metric scores. We propose a novel task-adaptive reconstruction framework that addresses this gap by incorporating a frozen pre-trained task network as a regularization term in the reconstruction loss function. Unlike existing joint-training approaches that simultaneously optimize both reconstruction and task networks, and risk diverging from satisfactory reconstructions, our method leverages a pre-trained task model to guide reconstruction training while still maintaining diagnostic quality. We validate our framework on a liver and liver tumor segmentation task. Our task-adaptive models achieve Dice scores up to 0.707, approaching the performance of full-dose scans (0.874), and substantially outperforming joint-training approaches (0.331) and traditional reconstruction methods (0.626). Critically, our framework can be integrated into any existing deep learning-based reconstruction model through simple loss function modification, enabling widespread adoption for task-adaptive optimization in clinical practice. Our codes are available at: https://github.com/itu-biai/task_adaptive_ct

低剂量CT任务自适应医学图像重建深度学习

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