arXiv:2511.07281cs.CV2025-11

用迁移学习自动分割脑卒中缺血病灶,提升准确率与效率。

Segmentation of Ischemic Stroke Lesions using Transfer Learning on Multi-sequence MRI

  • 基于Res-Unet框架,利用预训练权重进行迁移学习。
  • 在ISLES 2015数据集上达80.5%的Dice分数和74.03%准确率。
  • 融合多轴结果,适合医学影像自动化分析研究者使用。

准确理解缺血性脑卒中病灶对治疗和预后至关重要。磁共振成像(MRI)对急性缺血性脑卒中敏感,是常用诊断手段。然而,专家手动分割病灶耗时费力且易受主观差异影响。已有自动分析方法多依赖手工特征,难以捕捉病灶不规则、生理复杂的形态。本研究提出一种新框架,可快速自动分割T1加权、T2加权、DWI和FLAIR等多种MRI序列上的缺血性脑卒中病灶。模型在ISLES 2015脑卒中数据集上验证,采用Res-Unet架构两次训练:一次使用预训练权重,一次未使用,以探索迁移学习优势。评估指标包括体积级的Dice分数和灵敏度。最终通过多数投票分类器融合各轴分割结果,形成完整分割方案。实验结果显示,该方法取得80.5%的Dice分数和74.03%的准确率,证明其有效性。

原文摘要 · Abstract (English)

The accurate understanding of ischemic stroke lesions is critical for efficient therapy and prognosis of stroke patients. Magnetic resonance imaging (MRI) is sensitive to acute ischemic stroke and is a common diagnostic method for stroke. However, manual lesion segmentation performed by experts is tedious, time-consuming, and prone to observer inconsistency. Automatic medical image analysis methods have been proposed to overcome this challenge. However, previous approaches have relied on hand-crafted features that may not capture the irregular and physiologically complex shapes of ischemic stroke lesions. In this study, we present a novel framework for quickly and automatically segmenting ischemic stroke lesions on various MRI sequences, including T1-weighted, T2-weighted, DWI, and FLAIR. The proposed methodology is validated on the ISLES 2015 Brain Stroke sequence dataset, where we trained our model using the Res-Unet architecture twice: first, with pre-existing weights, and then without, to explore the benefits of transfer learning. Evaluation metrics, including the Dice score and sensitivity, were computed across 3D volumes. Finally, a Majority Voting Classifier was integrated to amalgamate the outcomes from each axis, resulting in a comprehensive segmentation method. Our efforts culminated in achieving a Dice score of 80.5\% and an accuracy of 74.03\%, showcasing the efficacy of our segmentation approach.

脑卒中图像分割迁移学习MRI

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