arXiv:2511.08418cs.LG2025-11中稿 · a poster presentat…被引 1

用物理约束神经算子模拟心脏电生理,高效且能泛化到不同网格和场景。

Physics-Informed Neural Operators for Cardiac Electrophysiology

  • 采用神经算子学习函数空间映射,不依赖固定网格。
  • 零样本迁移实现未见传播场景的准确预测,长期推演稳定。
  • 推理速度比传统求解器快,分辨率可提升10倍,适合临床仿真。

准确模拟由偏微分方程(PDE)支配的系统,如心脏电生理(EP)中的电压场,仍是建模难题。传统数值求解器计算成本高且对离散化敏感,而主流深度学习方法数据需求大,难以处理混沌动力学与长期预测。物理信息神经网络(PINNs)通过引入物理约束缓解部分问题,但仍受限于网格分辨率和长期预测稳定性。本文提出物理信息神经算子(PINO)方法求解心脏电生理中的PDE问题。与PINNs不同,PINO在函数空间间建模映射,可泛化至多种网格分辨率和初始条件。实验表明,PINO能准确复现长时间跨度的心脏电生理动态,涵盖训练中未见的传播情景,实现零样本评估;其在长序列滚动预测中保持高质量,且预测分辨率最高可达训练分辨率的10倍。相比数值求解器,模拟时间显著减少,凸显了PINO在高效、可扩展心脏电生理模拟中的潜力。

原文摘要 · Abstract (English)

Accurately simulating systems governed by PDEs, such as voltage fields in cardiac electrophysiology (EP) modelling, remains a significant modelling challenge. Traditional numerical solvers are computationally expensive and sensitive to discretisation, while canonical deep learning methods are data-hungry and struggle with chaotic dynamics and long-term predictions. Physics-Informed Neural Networks (PINNs) mitigate some of these issues by incorporating physical constraints in the learning process, yet they remain limited by mesh resolution and long-term predictive stability. In this work, we propose a Physics-Informed Neural Operator (PINO) approach to solve PDE problems in cardiac EP. Unlike PINNs, PINO models learn mappings between function spaces, allowing them to generalise to multiple mesh resolutions and initial conditions. Our results show that PINO models can accurately reproduce cardiac EP dynamics over extended time horizons and across multiple propagation scenarios, including zero-shot evaluations on scenarios unseen during training. Additionally, our PINO models maintain high predictive quality in long roll-outs (where predictions are recursively fed back as inputs), and can scale their predictive resolution by up to 10x the training resolution. These advantages come with a significant reduction in simulation time compared to numerical PDE solvers, highlighting the potential of PINO-based approaches for efficient and scalable cardiac EP simulations.

神经算子心脏电生理PDE求解物理信息

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