arXiv:2511.10014q-bio.QMcs.AI2025-11

快速构建生物医学文献知识图谱,处理速度超10倍提升

fastbmRAG: A Fast Graph-Based RAG Framework for Efficient Processing of Large-Scale Biomedical Literature

  • 分两阶段构建图谱:先用摘要粗建,再用正文精修
  • 相比现有工具提速超10倍,知识覆盖与准确率更高
  • 适合需要高效分析海量生物医学文献的研究者

大型语言模型(LLMs)正快速改变生物医学与医疗领域,从科研到新药发现均有巨大潜力。基于图的检索增强生成(RAG)系统可通过结构化实体与关系识别,提升长文本上下文推理能力,尤其适用于生物医学文献。尽管相较传统RAG有诸多优势,多数图RAG仍计算开销大,难以应用于大规模数据集。为此,我们提出fastbmRAG,一种专为生物医学文献优化的快速图基RAG框架。利用生物医学论文的规整结构,fastbmRAG将知识图谱构建分为两个阶段:首先基于摘要初步生成图谱;其次结合向量实体链接,以正文进行图谱精修,有效减少冗余与计算负载。评估表明,fastbmRAG比现有图RAG工具快10倍以上,并在知识覆盖与准确性上优于输入知识。该框架为大规模生物医学文献的快速理解、摘要生成与问答提供了高效解决方案。代码已开源:https://github.com/menggf/fastbmRAG。

原文摘要 · Abstract (English)

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation (RAG) systems, as a useful application of LLMs, can improve contextual reasoning through structured entity and relationship identification from long-context knowledge, e.g. biomedical literature. Even though many advantages over naive RAGs, most of graph-based RAGs are computationally intensive, which limits their application to large-scale dataset. To address this issue, we introduce fastbmRAG, an fast graph-based RAG optimized for biomedical literature. Utilizing well organized structure of biomedical papers, fastbmRAG divides the construction of knowledge graph into two stages, first drafting graphs using abstracts; and second, refining them using main texts guided by vector-based entity linking, which minimizes redundancy and computational load. Our evaluations demonstrate that fastbmRAG is over 10x faster than existing graph-RAG tools and achieve superior coverage and accuracy to input knowledge. FastbmRAG provides a fast solution for quickly understanding, summarizing, and answering questions about biomedical literature on a large scale. FastbmRAG is public available in https://github.com/menggf/fastbmRAG.

RAG知识图谱生物医学高效计算

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