arXiv:2511.11922cs.CLcs.LG2025-11

让大模型的诊断结果可解释,看清每部分病历的影响

Additive Large Language Models for Semi-Structured Text

  • 将文本分段后加权求和预测,每部分贡献可追踪
  • 在临床分类任务中性能接近传统大模型,解释性更强
  • 适合需要透明决策的医疗场景,助医生理解模型

大语言模型虽提升了临床文本分类性能,但其不可解释的预测限制了在科研与临床中的实际应用。为此,我们提出CALM(Classification with Additive Large Language Models),一种针对半结构化文本的可解释框架。输入如入院记录的章节或问诊表的问答字段,模型将输出视为各组件贡献的加和,使每个部分的影响融入前向计算过程,实现患者级与群体级的忠实解释。该加性结构支持清晰可视化,如类似广义加性模型的组件风险曲线,便于检查与沟通。尽管要求半结构化输入,许多临床文档天然具备此结构,自由文本也可自动提取。CALM在分类性能上媲美常规大模型,同时增强可信度,支持质量审计,并在模型开发与审查中揭示有意义的临床模式。

原文摘要 · Abstract (English)

Large Language Models have advanced clinical text classification, but their opaque predictions remain a critical barrier to practical adoption in research and clinical settings where investigators and physicians need to understand which parts of a patient's record drive risk signals. To address this challenge, we introduce \textbf{CALM}, short for \textbf{Classification with Additive Large Language Models}, an interpretable framework for semi-structured text where inputs are composed of semantically meaningful components, such as sections of an admission note or question-answer fields from an intake form. CALM predicts outcomes as the additive sum of each component's contribution, making these contributions part of the forward computation itself and enabling faithful explanations at both the patient and population level. The additive structure also enables clear visualizations, such as component-level risk curves similar to those used in generalized additive models, making the learned relationships easier to inspect and communicate. Although CALM expects semi-structured inputs, many clinical documents already have this form, and similar structure can often be automatically extracted from free-text notes. CALM achieves performance comparable to conventional LLM classifiers while improving trust, supporting quality-assurance checks, and revealing clinically meaningful patterns during model development and auditing.

可解释性医疗AI大模型

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