arXiv:2511.18422cs.CVcs.LG2025-11

用轻量模型精准分割脑肿瘤患者的增强MRI血管,助力手术规划。

NeuroVascU-Net: A Unified Multi-Scale and Cross-Domain Adaptive Feature Fusion U-Net for Precise 3D Segmentation of Brain Vessels in Contrast-Enhanced T1 MRI

  • 设计双模块融合网络,兼顾多尺度与跨域特征提取。
  • 在137例数据上达0.8609的骰子系数,参数仅1240万。
  • 适合临床部署,兼具高精度与低算力需求。

从增强T1 MRI中精确分割脑血管对神经外科手术规划至关重要。人工勾画耗时且存在观察者差异,现有自动化方法常以牺牲准确性换取计算效率,限制临床应用。本文提出NeuroVascU-Net,首个专为神经肿瘤患者标准T1CE MRI设计的深度学习分割架构,填补了以往以TOF-MRA为主的研究空白。该模型基于空洞U-Net,引入两个专用模块:瓶颈层的多尺度上下文特征融合(MSC²F)模块通过多尺度空洞卷积捕捉局部与全局信息;深层的跨域自适应特征融合(CDA²F)模块动态整合域特定特征,在保持低计算成本的同时提升表征能力。模型在137名脑瘤活检患者的标准T1CE扫描数据集上训练与验证,由注册功能神经外科医生标注。结果表明,该模型取得0.8609的骰子系数和0.8841的精确率,能准确分割主干及细小血管结构。其参数量仅为1240万,显著低于Swin U-NetR等基于Transformer的模型,兼顾精度与效率,是计算机辅助神经外科规划的理想解决方案。

原文摘要 · Abstract (English)

Precise 3D segmentation of cerebral vasculature from T1-weighted contrast-enhanced (T1CE) MRI is crucial for safe neurosurgical planning. Manual delineation is time-consuming and prone to inter-observer variability, while current automated methods often trade accuracy for computational cost, limiting clinical use. We present NeuroVascU-Net, the first deep learning architecture specifically designed to segment cerebrovascular structures directly from clinically standard T1CE MRI in neuro-oncology patients, addressing a gap in prior work dominated by TOF-MRA-based approaches. NeuroVascU-Net builds on a dilated U-Net and integrates two specialized modules: a Multi-Scale Contextual Feature Fusion ($MSC^2F$) module at the bottleneck and a Cross-Domain Adaptive Feature Fusion ($CDA^2F$) module at deeper hierarchical layers. $MSC^2F$ captures both local and global information via multi-scale dilated convolutions, while $CDA^2F$ dynamically integrates domain-specific features, enhancing representation while keeping computation low. The model was trained and validated on a curated dataset of T1CE scans from 137 brain tumor biopsy patients, annotated by a board-certified functional neurosurgeon. NeuroVascU-Net achieved a Dice score of 0.8609 and precision of 0.8841, accurately segmenting both major and fine vascular structures. Notably, it requires only 12.4M parameters, significantly fewer than transformer-based models such as Swin U-NetR. This balance of accuracy and efficiency positions NeuroVascU-Net as a practical solution for computer-assisted neurosurgical planning.

血管分割医学图像轻量模型U-Net

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