提出双层防御框架，同时对抗微调和零样本定制扩散模型的隐私泄露风险。

With the rapid advancement of diffusion models, a variety of fine-tuning methods have been developed, enabling high-fidelity image generation with high similarity to the target content using only 3 to 5 training images. More recently, zero-shot generation methods have emerged, capable of producing highly realistic outputs from a single reference image without altering model weights. However, technological advancements have also introduced significant risks to facial privacy. Malicious actors can exploit diffusion model customization with just a few or even one image of a person to create synthetic identities nearly identical to the original identity. Although research has begun to focus on defending against diffusion model customization, most existing defense methods target fine-tuning approaches and neglect zero-shot generation defenses. To address this issue, this paper proposes Dual-Layer Anti-Diffusion (DLADiff) to defense both fine-tuning methods and zero-shot methods. DLADiff contains a dual-layer protective mechanism. The first layer provides effective protection against unauthorized fine-tuning by leveraging the proposed Dual-Surrogate Models (DSUR) mechanism and Alternating Dynamic Fine-Tuning (ADFT), which integrates adversarial training with the prior knowledge derived from pre-fine-tuned models. The second layer, though simple in design, demonstrates strong effectiveness in preventing image generation through zero-shot methods. Extensive experimental results demonstrate that our method significantly outperforms existing approaches in defending against fine-tuning of diffusion models and achieves unprecedented performance in protecting against zero-shot generation.