融合六种可穿戴传感器,实现运动中精准无袖带血压监测。
Cuffless Blood Pressure Estimation from Six Wearable Sensor Modalities in Multi-Motion-State Scenarios
- 用六类传感器信号联合建模,提升运动状态下的血压估计鲁棒性。
- 在跑步、行走、静坐场景下,收缩压误差仅3.60毫米汞柱,舒张压3.01毫米汞柱。
- 通过对比学习与专家混合结构,适合长期健康监测与临床级应用。
心血管疾病是全球主要致病和致死原因,持续高血压常无症状,因此无袖带连续血压监测对早期筛查和长期管理至关重要。现有方法多仅依赖光电容积脉搏波(PPG)和心电图(ECG),且通常在静息或准静态条件下训练,难以维持多运动状态下的准确度。本研究提出一种六模态血压估计框架,融合ECG、多通道PPG、贴附压力、传感器温度及三轴加速度与角速度。每类信号由轻量分支编码器处理,对比学习实现跨模态语义对齐,混合专家(MoE)回归头自适应融合特征以输出不同运动状态下的血压。在公开的脉搏传导时间PPG数据集上,22名受试者包含跑步、步行、静坐数据的实验表明,该方法在收缩压(SBP)上平均绝对误差(MAE)为3.60 mmHg,舒张压(DBP)为3.01 mmHg。从临床角度,其在英国高血压学会(BHS)标准下均达A级,并满足美国医疗仪器协会(AAMI)标准对均值误差(ME)与误差标准差(SDE)的要求。
原文摘要 · Abstract (English)
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, and sustained hypertension is an often silent risk factor, making cuffless continuous blood pressure (BP) monitoring with wearable devices important for early screening and long-term management. Most existing cuffless BP estimation methods use only photoplethysmography (PPG) and electrocardiography (ECG) signals, alone or in combination. These models are typically developed under resting or quasi-static conditions and struggle to maintain robust accuracy in multi-motion-state scenarios. In this study, we propose a six-modal BP estimation framework that jointly leverages ECG, multi-channel PPG, attachment pressure, sensor temperature, and triaxial acceleration and angular velocity. Each modality is processed by a lightweight branch encoder, contrastive learning enforces cross-modal semantic alignment, and a mixture-of-experts (MoE) regression head adaptively maps the fused features to BP across motion states. Comprehensive experiments on the public Pulse Transit Time PPG Dataset, which includes running, walking, and sitting data from 22 subjects, show that the proposed method achieves mean absolute errors (MAE) of 3.60 mmHg for systolic BP (SBP) and 3.01 mmHg for diastolic BP (DBP). From a clinical perspective, it attains Grade A for SBP, DBP, and mean arterial pressure (MAP) according to the British Hypertension Society (BHS) protocol and meets the numerical criteria of the Association for the Advancement of Medical Instrumentation (AAMI) standard for mean error (ME) and standard deviation of error (SDE).
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