arXiv:2512.03098q-bio.QMcs.LG2025-12中稿 · IEEE BHI 2025

在大型儿科医疗系统中构建可信AI数据流程,提升真实世界应用能力

An AI Implementation Science Study to Improve Trustworthy Data in a Large Healthcare System

  • 基于Python构建数据质量评估工具,对接医院现有系统
  • 通过METRIC框架整合可信AI原则,解决缺失值、冗余等质量问题
  • 对比系统化与场景化两种实施策略,探索混合型落地路径

人工智能在医疗领域的快速发展催生了对可信AI与实施科学的需求。本研究以大型多中心儿科医疗机构Shriners Childrens(SC)为案例,将机构研究数据仓库(RDW)现代化升级至OMOP CDM v5.4,并部署于安全的Microsoft Fabric环境。我们开发了一款兼容SC基础设施的Python数据质量评估工具,扩展了OHDsi原有的R/Java版数据质量仪表盘(DQD),引入可信AI的METRIC框架,重点改进了信息性缺失、数据冗余、时效性及分布一致性等问题。同时,基于FHIR标准,对颅面微小畸形(CFM)病例比较了系统性与场景定制化的AI实施策略。研究贡献包括:真实世界中的AI实施评估、可信AI原则与数据质量评估融合、以及结合系统化基础与场景驱动的混合实施模式,推动医疗AI落地。

原文摘要 · Abstract (English)

The rapid growth of Artificial Intelligence (AI) in healthcare has sparked interest in Trustworthy AI and AI Implementation Science, both of which are essential for accelerating clinical adoption. However, strict regulations, gaps between research and clinical settings, and challenges in evaluating AI systems continue to hinder real-world implementation. This study presents an AI implementation case study within Shriners Childrens (SC), a large multisite pediatric system, showcasing the modernization of SCs Research Data Warehouse (RDW) to OMOP CDM v5.4 within a secure Microsoft Fabric environment. We introduce a Python-based data quality assessment tool compatible with SCs infrastructure, extending OHDsi's R/Java-based Data Quality Dashboard (DQD) and integrating Trustworthy AI principles using the METRIC framework. This extension enhances data quality evaluation by addressing informative missingness, redundancy, timeliness, and distributional consistency. We also compare systematic and case-specific AI implementation strategies for Craniofacial Microsomia (CFM) using the FHIR standard. Our contributions include a real-world evaluation of AI implementations, integration of Trustworthy AI principles into data quality assessment, and insights into hybrid implementation strategies that blend systematic infrastructure with use-case-driven approaches to advance AI in healthcare.

可信AI医疗数据实施科学

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