提出新模型,让医学影像分割更准更稳,尤其适合光照不均的图像。
RefLSM: Linearized Structural-Prior Reflectance Model for Medical Image Segmentation and Bias-Field Correction
- 用光照无关的反射率分解代替传统方法,保留细节。
- 引入线性结构先验和松弛二值水平集,提升抗噪与边界精度。
- 适合处理光照不均、边界模糊的医学图像,计算快结果好。
医学图像分割受强度不均、噪声、边界模糊和结构不规则等影响仍具挑战。传统水平集方法依赖近似偏置场估计,在严重非均匀成像条件下表现不佳。为此,我们提出一种新型变分反射率基水平集模型(RefLSM),将受Retinex启发的反射率分解直接融入分割框架。通过将观测图像分解为反射率与偏置场成分,RefLSM直接对反射率进行分割,该成分对光照不变且能保留细小结构。在此基础上,提出两项关键创新:其一,引入线性结构先验,引导平滑反射率梯度朝向数据驱动参考,为噪声或低对比度场景提供可靠几何引导;其二,嵌入松弛二值水平集,并通过凸松弛与符号投影强制实现,确保演化稳定,避免重初始化引起的扩散。变分问题采用基于ADMM的优化方案高效求解。在多个医学影像数据集上的大量实验表明,RefLSM在分割精度、鲁棒性与计算效率方面均优于现有先进水平集方法。
原文摘要 · Abstract (English)
Medical image segmentation remains challenging due to intensity inhomogeneity, noise, blurred boundaries, and irregular structures. Traditional level set methods, while effective in certain cases, often depend on approximate bias field estimations and therefore struggle under severe non-uniform imaging conditions. To address these limitations, we propose a novel variational Reflectance-based Level Set Model (RefLSM), which explicitly integrates Retinex-inspired reflectance decomposition into the segmentation framework. By decomposing the observed image into reflectance and bias field components, RefLSM directly segments the reflectance, which is invariant to illumination and preserves fine structural details. Building on this foundation, we introduce two key innovations for enhanced precision and robustness. First, a linear structural prior steers the smoothed reflectance gradients toward a data-driven reference, providing reliable geometric guidance in noisy or low-contrast scenes. Second, a relaxed binary level-set is embedded in RefLSM and enforced via convex relaxation and sign projection, yielding stable evolution and avoiding reinitialization-induced diffusion. The resulting variational problem is solved efficiently using an ADMM-based optimization scheme. Extensive experiments on multiple medical imaging datasets demonstrate that RefLSM achieves superior segmentation accuracy, robustness, and computational efficiency compared to state-of-the-art level set methods.
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