为健康类大模型开发提供安全可信赖的评估框架
A Principle-based Framework for the Development and Evaluation of Large Language Models for Health and Wellness
- 基于安全、有用性等五大原则构建评估体系
- 在超1.3万名用户中验证,发现初始测试未暴露的问题
- 适合医疗AI开发者与监管者参考
将生成式人工智能引入个人健康应用,为个性化健康指导带来变革机遇,同时也带来用户安全、模型准确性和隐私保护等挑战。为此,本文提出并验证了一套基于原则的系统化评估框架,用于评价应用于个人健康与福祉的大语言模型。首先介绍了Fitbit Insights Explorer这一由大语言模型驱动的系统,帮助用户解读个人健康数据。随后提出了包含安全性、有用性、准确性、相关性与个性化(SHARP)五个维度的原则框架,整合了普通用户与临床专家的人工评估、自动评分及对抗测试,形成迭代开发流程。该框架在涉及超过13,000名知情同意用户的分阶段部署中得到应用,成功识别出初期测试未能发现的问题,并指导针对性优化。研究证明,必须将孤立的技术评估与真实用户反馈相结合。最终建立了一套可操作的责任型开发与部署方法,为保障新兴技术的安全性、有效性与可信度提供了标准化路径。
原文摘要 · Abstract (English)
The incorporation of generative artificial intelligence into personal health applications presents a transformative opportunity for personalized, data-driven health and fitness guidance, yet also poses challenges related to user safety, model accuracy, and personal privacy. To address these challenges, a novel, principle-based framework was developed and validated for the systematic evaluation of LLMs applied to personal health and wellness. First, the development of the Fitbit Insights explorer, a large language model (LLM)-powered system designed to help users interpret their personal health data, is described. Subsequently, the safety, helpfulness, accuracy, relevance, and personalization (SHARP) principle-based framework is introduced as an end-to-end operational methodology that integrates comprehensive evaluation techniques including human evaluation by generalists and clinical specialists, autorater assessments, and adversarial testing, into an iterative development lifecycle. Through the application of this framework to the Fitbit Insights explorer in a staged deployment involving over 13,000 consented users, challenges not apparent during initial testing were systematically identified. This process guided targeted improvements to the system and demonstrated the necessity of combining isolated technical evaluations with real-world user feedback. Finally, a comprehensive, actionable approach is established for the responsible development and deployment of LLM-powered health applications, providing a standardized methodology to foster innovation while ensuring emerging technologies are safe, effective, and trustworthy for users.
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