用可穿戴设备生成数字人,预测中风患者上下坡和爬楼梯能力。
Wearable-informed generative digital avatars predict task-conditioned post-stroke locomotion
- 融合可穿戴数据与物理模型,生成个性化运动数字人。
- 预测姿势与真实动作相似度达82.2%(斜坡)和69.9%(台阶)。
- 帮助康复训练更精准,提升患者功能评分,适合临床康复应用。
中风后动态预测行走能力可实现更个性化的康复,但现有评估多为静态损伤评分,无法判断患者能否完成特定任务如上坡或爬楼梯。本文提出一种结合可穿戴惯性传感与数据-物理混合的生成框架,从单次20米平地行走(5个IMU记录)重建中风患者的运动控制,并预测其在新环境中的任务相关步态。该框架利用健康运动先验与混合模仿学习,个性化构建物理驱动的数字人,生成符合动力学可行性的倾斜行走与台阶通过动作。在11名中风患者中,预测姿态对斜坡和台阶的相似度分别达82.2%和69.9%,显著优于纯物理基线。一项多中心试点随机研究(n=21;28天)显示,使用场景化步态预测指导任务选择与难度调节,相比常规护理带来更大功能改善(Fugl-Meyer下肢评分平均提升6.0 vs 3.7分;p<0.05)。结果表明,可穿戴信息驱动的生成数字人有望增强个性化步态康复规划,推动动态个性化中风运动恢复策略的发展。
原文摘要 · Abstract (English)
Dynamic prediction of locomotor capacity after stroke could enable more individualized rehabilitation, yet current assessments largely provide static impairment scores and do not indicate whether patients can perform specific tasks such as slope walking or stair climbing. Here, we present a wearable-informed data-physics hybrid generative framework that reconstructs a stroke survivor's locomotor control from wearable inertial sensing and predicts task-conditioned post-stroke locomotion in new environments. From a single 20 m level-ground walking trial recorded by five IMUs, the framework personalizes a physics-based digital avatar using a healthy-motion prior and hybrid imitation learning, generating dynamically feasible, patient-specific movements for inclined walking and stair negotiation. Across 11 stroke inpatients, predicted postures reached 82.2% similarity for slopes and 69.9% for stairs, substantially exceeding a physics-only baseline. In a multicentre pilot randomized study (n = 21; 28 days), access to scenario-specific locomotion predictions to support task selection and difficulty titration was associated with larger gains in Fugl-Meyer lower-extremity scores than standard care (mean change 6.0 vs 3.7 points; $p < 0.05$). These results suggest that wearable-informed generative digital avatars may augment individualized gait rehabilitation planning and provide a pathway toward dynamically personalized post-stroke motor recovery strategies.
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