arXiv:2512.15061eess.IVcs.AI2025-12被引 1

用少量标注图精准分割眼底图像中的视盘和视杯,助力青光眼诊断。

Meta-learners for few-shot weakly-supervised optic disc and cup segmentation on fundus images

  • 设计新型元学习框架,支持极少数样本下的弱监督分割。
  • 仅用一张稀疏标注图即达88.15%视盘分割精度,超越多数需更多标注的方法。
  • 模型轻量高效,参数少于200万,无需重训练,适合临床部署。

本研究针对青光眼诊断中视盘(OD)和视杯(OC)分割因标注数据有限带来的挑战,提出面向少样本弱监督分割(FWS)的元学习方法。通过引入Omni元训练策略,在平衡数据利用与多样化样本数量方面显著提升现有方法性能,并开发计算成本更低的高效版本。同时,提出稀疏化技术,生成更可定制、更具代表性的涂抹标记等稀疏标签。在多个数据集上评估显示,Omni及高效版本均优于原始方法,其中最优模型Efficient Omni ProtoSeg(EO-ProtoSeg)在REFUGE数据集上仅用一张稀疏标注图像即实现视盘88.15%、视杯71.17%的交并比(IoU),超越需更多标注的少样本与半监督方法。其最佳表现达DRISHTIGS上86.80%(OD)、71.78%(OC),REFUGE上88.21%(OD)、73.70%(OC),REFUGE上80.39%(OD)、52.65%(OC)。EO-ProtoSeg性能媲美无监督域适应方法,但参数少于两百万且无需重训练。

原文摘要 · Abstract (English)

This study develops meta-learners for few-shot weakly-supervised segmentation (FWS) to address the challenge of optic disc (OD) and optic cup (OC) segmentation for glaucoma diagnosis with limited labeled fundus images. We significantly improve existing meta-learners by introducing Omni meta-training which balances data usage and diversifies the number of shots. We also develop their efficient versions that reduce computational costs. In addition, we develop sparsification techniques that generate more customizable and representative scribbles and other sparse labels. After evaluating multiple datasets, we find that Omni and efficient versions outperform the original versions, with the best meta-learner being Efficient Omni ProtoSeg (EO-ProtoSeg). It achieves intersection over union (IoU) scores of 88.15% for OD and 71.17% for OC on the REFUGE dataset using just one sparsely labeled image, outperforming few-shot and semi-supervised methods which require more labeled images. Its best performance reaches 86.80% for OD and 71.78%for OC on DRISHTIGS, 88.21% for OD and 73.70% for OC on REFUGE, 80.39% for OD and 52.65% for OC on REFUGE. EO-ProtoSeg is comparable to unsupervised domain adaptation methods yet much lighter with less than two million parameters and does not require any retraining.

医学图像分割少样本学习弱监督眼科影像

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