arXiv:2512.15762cs.LGcs.AI2025-12AAAI被引 1

通过借用他人数据提升手术低血压预测的个性化精度。

Cross-Sample Augmented Test-Time Adaptation for Personalized Intraoperative Hypotension Prediction

  • 利用跨患者数据构建样本库,增强罕见事件的训练信号。
  • 在零样本场景下召回率提升7.46%,F1提升5.07%。
  • 适合临床实时预警系统,尤其适用于低事件发生率场景。

术中低血压(IOH)威胁手术安全,但因患者个体差异大,准确预测仍具挑战。尽管测试时自适应(TTA)为个性化预测提供了新思路,但低血压事件稀少导致测试时训练不可靠。为此,本文提出跨样本增强的测试时自适应框架CSA-TTA:首先将历史数据按是否低血压分割,构建跨患者样本库;接着采用粗到细检索策略——先用K-Shape聚类提取代表性中心,再根据当前患者信号检索最相似的前K个样本;同时在训练中融合自监督掩码重建与回溯序列预测信号,提升模型对术中快速细微变化的适应能力。在VitalDB和真实院内数据集上,集成TimesFM与UniTS等先进时序模型进行评估,结果表明:在微调场景下,召回率与F1分别提升1.33%和1.13%;在零样本场景下,分别提升7.46%和5.07%,展现强大鲁棒性与泛化能力。

原文摘要 · Abstract (English)

Intraoperative hypotension (IOH) poses significant surgical risks, but accurate prediction remains challenging due to patient-specific variability. While test-time adaptation (TTA) offers a promising approach for personalized prediction, the rarity of IOH events often leads to unreliable test-time training. To address this, we propose CSA-TTA, a novel Cross-Sample Augmented Test-Time Adaptation framework that enhances training by incorporating hypotension events from other individuals. Specifically, we first construct a cross-sample bank by segmenting historical data into hypotensive and non-hypotensive samples. Then, we introduce a coarse-to-fine retrieval strategy for building test-time training data: we initially apply K-Shape clustering to identify representative cluster centers and subsequently retrieve the top-K semantically similar samples based on the current patient signal. Additionally, we integrate both self-supervised masked reconstruction and retrospective sequence forecasting signals during training to enhance model adaptability to rapid and subtle intraoperative dynamics. We evaluate the proposed CSA-TTA on both the VitalDB dataset and a real-world in-hospital dataset by integrating it with state-of-the-art time series forecasting models, including TimesFM and UniTS. CSA-TTA consistently enhances performance across settings-for instance, on VitalDB, it improves Recall and F1 scores by +1.33% and +1.13%, respectively, under fine-tuning, and by +7.46% and +5.07% in zero-shot scenarios-demonstrating strong robustness and generalization.

医疗预测测试时自适应时序建模个性化

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