arXiv:2512.17340stat.MEcs.CY2025-12

针对慢性肾病多群体公平性问题,提出可高效实现的惩罚式公平回归方法。

Penalized Fair Regression for Multiple Groups in Chronic Kidney Disease

  • 通过真阳性率差异惩罚项,构建多群体公平回归框架
  • 在模拟和真实数据中均实现公平性与准确性的更好平衡
  • 适用于存在系统性医疗偏见的群体,如不同种族患者

公平回归方法有望缓解医疗领域中的社会偏见问题,但针对多个群体偏见的惩罚式公平回归研究仍不足。本文提出一种通用回归框架,通过多群体不公平惩罚项解决该问题,特别针对二分类结果引入真阳性率差异惩罚。该方法可通过转化为成本敏感分类问题高效实现。此外,提出新型评分函数以自动选择惩罚权重。在模拟实验中,所提方法实现了超越现有对比方法的公平性-准确性权衡。最后,将其应用于全国多中心初级保健研究中的慢性肾病数据,构建终末期肾病的公平分类器。结果显示,多种族/民族群体的公平性显著提升,且整体拟合度未明显下降。

原文摘要 · Abstract (English)

Fair regression methods have the potential to mitigate societal bias concerns in health care, but there has been little work on penalized fair regression when multiple groups experience such bias. We propose a general regression framework that addresses this gap with unfairness penalties for multiple groups. Our approach is demonstrated for binary outcomes with true positive rate disparity penalties. It can be efficiently implemented through reduction to a cost-sensitive classification problem. We additionally introduce novel score functions for automatically selecting penalty weights. Our penalized fair regression methods are empirically studied in simulations, where they achieve a fairness-accuracy frontier beyond that of existing comparison methods. Finally, we apply these methods to a national multi-site primary care study of chronic kidney disease to develop a fair classifier for end-stage renal disease. There we find substantial improvements in fairness for multiple race and ethnicity groups who experience societal bias in the health care system without any appreciable loss in overall fit.

公平机器学习医疗健康回归分析慢性肾病

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