arXiv:2512.18737cs.LGcs.AI2025-12

利用治疗后变量提升个体治疗效应估计精度

PIPCFR: Pseudo-outcome Imputation with Post-treatment Variables for Individual Treatment Effect Estimation

  • 引入治疗后变量改进伪结果插补方法
  • 在真实与模拟数据上显著降低预测误差
  • 适合关注因果推断与个性化决策的研究者

个体治疗效应(ITE)估计旨在预测治疗变化带来的结果差异。观察性数据中的根本挑战在于:虽需推断不同治疗下的结果差异,但每个个体仅能观测到单一治疗下的结果。现有方法或通过推断伪结果训练,或构建匹配实例对。然而,近期研究普遍忽视了治疗后变量对结果的影响,导致无法充分捕捉结果变异,进而增加反事实预测方差。本文提出伪结果插补结合治疗后变量的反事实回归方法(PIPCFR),首次系统分析治疗后变量的使用挑战,并建立新的ITE风险理论边界,明确揭示其与估计精度的关系。相较于忽略或强假设处理这些变量的方法,PIPCFR学习有效表征,在保留信息的同时缓解偏差。在真实世界和模拟数据上的实证评估表明,该方法显著优于现有技术。

原文摘要 · Abstract (English)

The estimation of individual treatment effects (ITE) focuses on predicting the outcome changes that result from a change in treatment. A fundamental challenge in observational data is that while we need to infer outcome differences under alternative treatments, we can only observe each individual's outcome under a single treatment. Existing approaches address this limitation either by training with inferred pseudo-outcomes or by creating matched instance pairs. However, recent work has largely overlooked the potential impact of post-treatment variables on the outcome. This oversight prevents existing methods from fully capturing outcome variability, resulting in increased variance in counterfactual predictions. This paper introduces Pseudo-outcome Imputation with Post-treatment Variables for Counterfactual Regression (PIPCFR), a novel approach that incorporates post-treatment variables to improve pseudo-outcome imputation. We analyze the challenges inherent in utilizing post-treatment variables and establish a novel theoretical bound for ITE risk that explicitly connects post-treatment variables to ITE estimation accuracy. Unlike existing methods that ignore these variables or impose restrictive assumptions, PIPCFR learns effective representations that preserve informative components while mitigating bias. Empirical evaluations on both real-world and simulated datasets demonstrate that PIPCFR achieves significantly lower ITE errors compared to existing methods.

因果推断个体效应伪结果

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