基于DeepSeek的AI系统提升胸片诊断效率,临床验证效果优于大模型。
A DeepSeek-Powered AI System for Automated Chest Radiograph Interpretation in Clinical Practice
- 用轻量级优化的DeepSeek模型实现胸片报告自动生成。
- 临床试验中报告质量提升,解读时间减少18.3%,专家偏好率达54.3%。
- 适合资源有限地区推广,开源架构助力AI放射科落地。
全球放射科医生短缺问题因胸片工作量巨大而加剧,尤其在基层医疗中更为突出。尽管多模态大语言模型展现潜力,但现有评估多依赖自动化指标或回顾性分析,缺乏严格的前瞻性临床验证。本文基于DeepSeek Janus-Pro模型开发了Janus-Pro-CXR(1B)胸片解读系统,并通过多中心前瞻性试验(NCT07117266)进行严格验证。该系统在报告生成方面超越当前最优模型,表现优于更大参数量的ChatGPT 4o(200B参数),并能可靠检测六类关键影像学异常。回顾性评估显示其报告准确率显著高于Janus-Pro和ChatGPT 4o。在前瞻性临床部署中,AI辅助使报告质量评分提升,解读时间缩短18.3%(P < 0.001),专家在54.3%的案例中更倾向使用。通过轻量化架构与领域优化,系统显著提升诊断可靠性与工作效率,尤其适用于资源受限环境。模型架构与实现框架将开源,推动AI辅助放射学临床转化。
原文摘要 · Abstract (English)
A global shortage of radiologists has been exacerbated by the significant volume of chest X-ray workloads, particularly in primary care. Although multimodal large language models show promise, existing evaluations predominantly rely on automated metrics or retrospective analyses, lacking rigorous prospective clinical validation. Janus-Pro-CXR (1B), a chest X-ray interpretation system based on DeepSeek Janus-Pro model, was developed and rigorously validated through a multicenter prospective trial (NCT07117266). Our system outperforms state-of-the-art X-ray report generation models in automated report generation, surpassing even larger-scale models including ChatGPT 4o (200B parameters), while demonstrating reliable detection of six clinically critical radiographic findings. Retrospective evaluation confirms significantly higher report accuracy than Janus-Pro and ChatGPT 4o. In prospective clinical deployment, AI assistance significantly improved report quality scores, reduced interpretation time by 18.3% (P < 0.001), and was preferred by a majority of experts in 54.3% of cases. Through lightweight architecture and domain-specific optimization, Janus-Pro-CXR improves diagnostic reliability and workflow efficiency, particularly in resource-constrained settings. The model architecture and implementation framework will be open-sourced to facilitate the clinical translation of AI-assisted radiology solutions.
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