arXiv:2512.20481q-bio.NCcs.CL2025-12

大脑用两种不同节奏处理语言连贯性:慢积累与快切换。

Coherence in the brain unfolds across separable temporal regimes

  • 用大语言模型提取无标注的语义漂移和事件切换信号。
  • 慢速漂移信号集中在默认模式网络,快速切换信号在听觉皮层明显。
  • 为精神疾病语言障碍研究提供神经机制新视角。

为维持语言连贯性,大脑需兼顾长期语境意义的逐步积累(漂移)与事件边界处表征的快速重组(切换)。这两种过程在自然语言聆听中的神经实现仍不明确。本研究测试了是否可通过无标注的漂移与切换信号捕捉二者,并探究其在脑区中的分布差异。信号源自大语言模型对叙事输入的处理。通过在7特斯拉fMRI下对一名健康成人连续监听超过7小时犯罪故事,实现高精度体素级编码模型,采用正则化编码框架建模特征引导的血流动力学响应,并在独立故事上验证。漂移预测在默认模式网络枢纽广泛存在,而切换预测在双侧初级听觉皮层和语言关联皮层显著。结果表明,语言理解中的连贯性由缓慢上下文整合与快速事件驱动重组两种分离但共现的神经机制实现,为精神疾病中语言连贯性障碍提供了机制切入点。

原文摘要 · Abstract (English)

To maintain coherence in language, the brain must satisfy key competing temporal demands: the gradual accumulation of meaning across extended context (drift) and the rapid reconfiguration of representations at event boundaries (shift). How these processes are implemented in the human brain during naturalistic listening remains unclear. Here, we tested whether both can be captured by annotation-free drift and shift signals and whether their neural expression shows distinct regional preferences across the brain. These signals were derived from a large language model (LLM) processing the narrative input. To enable high-precision voxelwise encoding models with stable parameter estimates, we densely sampled one healthy adult across more than 7 hours of listening to crime stories while collecting 7 Tesla fMRI data. We then modeled the feature-informed hemodynamic response using a regularized encoding framework validated on independent stories. Drift predictions were prevalent in default-mode network hubs, whereas shift predictions were evident bilaterally in the primary auditory cortex and language association cortex. Together, these findings show that coherence during language comprehension is implemented through distinct but co-expressed neural regimes of slow contextual integration and rapid event-driven reconfiguration, offering a mechanistic entry point for understanding disturbances of language coherence in psychiatric disorders.

语言理解神经机制脑成像

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