提出新敏感性分析方法,检验隐藏治疗版本对因果推断的影响。
Sensitivity Analysis of the Consistency Assumption
- 引入新数学符号区分协变量与治疗版本
- 针对隐藏治疗版本导致的偏差进行敏感性评估
- 适用于手术等存在隐性治疗差异的场景
敏感性分析通过评估结论对假设偏离的敏感程度,辅助因果推断。一致性假设要求不存在隐藏的治疗版本,且自然状态下的结果等于干预后的结果。在手术情境中,基因特征是协变量,而特定外科医生的技术水平则是治疗版本。现实中可能存在未观测到的治疗版本,本文提出一种新型敏感性分析方法,专门应对由隐藏治疗版本引起的混杂问题。不同于传统方法关注未测量协变量的混杂,本文聚焦于隐藏治疗版本的干扰。论文引入新的数学符号以支持该方法,并给出了具体应用示例。
原文摘要 · Abstract (English)
Sensitivity analysis informs causal inference by assessing the sensitivity of conclusions to departures from assumptions. The consistency assumption states that there are no hidden versions of treatment and that the outcome arising naturally equals the outcome arising from intervention. When reasoning about the possibility of consistency violations, it can be helpful to distinguish between covariates and versions of treatment. In the context of surgery, for example, genomic variables are covariates and the skill of a particular surgeon is a version of treatment. There may be hidden versions of treatment, and this paper addresses that concern with a new kind of sensitivity analysis. Whereas many methods for sensitivity analysis are focused on confounding by unmeasured covariates, the methodology of this paper is focused on confounding by hidden versions of treatment. In this paper, new mathematical notation is introduced to support the novel method, and example applications are described.
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