用AI分析癌症研究合作模式,帮团队更高效组队。
Interpretable Link Prediction in AI-Driven Cancer Research: Uncovering Co-Authorship Patterns
- 构建36个作者合作网络,结合属性与结构特征预测合作类型。
- 随机森林模型对新、持续、中断合作的召回率最高。
- 学科相似性越高,合作越可能成立;高产和资历深反而易导致合作中断。
人工智能正在重塑癌症诊断与治疗。该疾病复杂,需跨领域专家协作以保障研究成效。尽管重要,但组建有效跨学科团队仍具挑战。理解并预测合作模式有助于研究人员、机构及政策制定者优化资源配置,推动有影响力的科研。本研究以共作者网络为代理指标,分析人工智能驱动的癌症研究合作。基于Scopus数据库2000-2017年7,738篇论文,构建了36个重叠的共作者网络,涵盖新出现、持续存在和已中断的合作关系。我们提取了基于属性与结构的特征,并训练了四种机器学习分类器。通过SHAP方法实现模型可解释性分析。结果显示,随机森林在三类合作模式上的召回率均最高。学科相似性得分是关键因素:对新合作与持续合作呈正向影响,对中断合作呈负向影响。此外,高产出和高资历与合作中断呈正相关。研究结果可指导高效科研团队组建,促进跨学科协作,支持战略决策。
原文摘要 · Abstract (English)
Artificial intelligence (AI) is transforming cancer diagnosis and treatment. The intricate nature of this disease necessitates the collaboration of diverse stakeholders with varied expertise to ensure the effectiveness of cancer research. Despite its importance, forming effective interdisciplinary research teams remains challenging. Understanding and predicting collaboration patterns can help researchers, organizations, and policymakers optimize resources and foster impactful research. We examined co-authorship networks as a proxy for collaboration within AI-driven cancer research. Using 7,738 publications (2000-2017) from Scopus, we constructed 36 overlapping co-authorship networks representing new, persistent, and discontinued collaborations. We engineered both attribute-based and structure-based features and built four machine learning classifiers. Model interpretability was performed using Shapley Additive Explanations (SHAP). Random forest achieved the highest recall for all three types of examined collaborations. The discipline similarity score emerged as a crucial factor, positively affecting new and persistent patterns while negatively impacting discontinued collaborations. Additionally, high productivity and seniority were positively associated with discontinued links. Our findings can guide the formation of effective research teams, enhance interdisciplinary cooperation, and inform strategic policy decisions.
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