联合注册与分割,提升脑皮层分区精度
JParc: Joint cortical surface parcellation with registration
- 联合优化皮层配准与分区,利用几何特征改进标签传播
- 在Mindboggle数据集上Dice分数超90%,仅用折叠模式特征
- 适合脑图谱构建、手术规划等需要高精度分区的场景
皮层表面分区是基础神经科学研究和临床应用中的核心任务,有助于更精确地定位脑区。基于模型和学习的方法可实现自动化分区,减少人工标注需求。尽管分区性能不断提升,但现有学习方法往往脱离配准与模板传播,未解释其相比传统方法的优势。本文提出JParc框架,联合进行皮层配准与分区,在严格实验中证明其性能优于当前最优方法。性能提升主要源于精准的皮层配准和学习得到的分区模板。通过浅层子网络微调传播后的模板标签,JParc仅使用基本几何特征(沟回深度、曲率)即在Mindboggle数据集上取得超过90%的Dice分数。该方法显著提升脑图谱研究的统计效能,并支持手术规划等下游神经科学与临床应用。
原文摘要 · Abstract (English)
Cortical surface parcellation is a fundamental task in both basic neuroscience research and clinical applications, enabling more accurate mapping of brain regions. Model-based and learning-based approaches for automated parcellation alleviate the need for manual labeling. Despite the advancement in parcellation performance, learning-based methods shift away from registration and atlas propagation without exploring the reason for the improvement compared to traditional methods. In this study, we present JParc, a joint cortical registration and parcellation framework, that outperforms existing state-of-the-art parcellation methods. In rigorous experiments, we demonstrate that the enhanced performance of JParc is primarily attributable to accurate cortical registration and a learned parcellation atlas. By leveraging a shallow subnetwork to fine-tune the propagated atlas labels, JParc achieves a Dice score greater than 90% on the Mindboggle dataset, using only basic geometric features (sulcal depth, curvature) that describe cortical folding patterns. The superior accuracy of JParc can significantly increase the statistical power in brain mapping studies as well as support applications in surgical planning and many other downstream neuroscientific and clinical tasks.
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