arXiv:2601.00981cs.ROcs.CV2026-01被引 2

用MRI磁场控制磁性器械,实现无绳靶向治疗的术前模拟平台。

Simulations of MRI Guided and Powered Ferric Applicators for Tetherless Delivery of Therapeutic Interventions

  • 通过MRI数据构建血管虚拟通道,防止器械穿孔或碰撞。
  • 根据血流和磁场梯度约束生成安全操控波形,支持多流速模拟。
  • 适合介入手术规划、医疗器械研发人员使用。

磁共振成像(MRI)是术前规划的成熟技术,也正在探索用于血管介入等术中引导。本研究提出一种计算平台,用于术前规划与建模基于MRI驱动的磁性器械在血管内的运动。该平台采用双向数据与指令管道,连接MRI扫描仪、计算核心与操作员。首先处理多层MR数据提取血管网络,并在血管内拟合虚拟走廊(VF),作为器械不可进入区域以避免血管穿孔或碰撞。利用血管中心线、虚拟走廊及MRI安全限制(dB/dt、最大梯度)生成磁场梯度波形。用户可选择不同血流剖面,用于模拟器械运动。建模模块进一步提供路径是否安全的判断提示。为支持未来实时操作,平台基于Qt框架(C/C++)实现,各功能模块(如PID控制器、虚拟走廊生成、梯度波形生成)在独立线程运行。

原文摘要 · Abstract (English)

Magnetic Resonance Imaging (MRI) is a well-established modality for pre-operative planning and is also explored for intra-operative guidance of procedures such as intravascular interventions. Among the experimental robot-assisted technologies, the magnetic field gradients of the MRI scanner are used to power and maneuver ferromagnetic applicators for accessing sites in the patient's body via the vascular network. In this work, we propose a computational platform for preoperative planning and modeling of MRI-powered applicators inside blood vessels. This platform was implemented as a two-way data and command pipeline that links the MRI scanner, the computational core, and the operator. The platform first processes multi-slice MR data to extract the vascular bed and then fits a virtual corridor inside the vessel. This corridor serves as a virtual fixture (VF), a forbidden region for the applicators to avoid vessel perforation or collision. The geometric features of the vessel centerline, the VF, and MRI safety compliance (dB/dt, max available gradient) are then used to generate magnetic field gradient waveforms. Different blood flow profiles can be user-selected, and those parameters are used for modeling the applicator's maneuvering. The modeling module further generates cues about whether the selected vascular path can be safely maneuvered. Given future experimental studies that require a real-time operation, the platform was implemented on the Qt framework (C/C++) with software modules performing specific tasks running on dedicated threads: PID controller, generation of VF, generation of MR gradient waveforms.

MRI引导血管介入虚拟走廊术前模拟

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