arXiv:2601.04676cs.CV2026-01

针对胰腺CT分割难题,提出双分支多尺度Mamba网络,提升边界与小病灶精度。

DB-MSMUNet:Dual Branch Multi-scale Mamba UNet for Pancreatic CT Scans Segmentation

  • 采用多尺度Mamba模块融合形变卷积与状态空间建模,增强全局与局部特征建模。
  • 双解码器设计:边缘解码器强化边界,区域解码器保留细粒度结构,精准重建小病灶。
  • 多尺度辅助监督机制提升梯度反馈,显著改善小目标分割鲁棒性,适合临床实用。

准确分割CT图像中的胰腺及其病灶对胰腺癌的精准诊断和治疗至关重要。然而,由于组织对比度低、解剖边界模糊、器官形状不规则及病灶尺寸小等因素,该任务仍具挑战性。为此,本文提出DB-MSMUNet(双分支多尺度Mamba UNet),一种专为胰腺分割设计的新型编码器-解码器架构。编码器基于多尺度Mamba模块(MSMM),结合可变形卷积与多尺度状态空间建模,提升全局上下文感知与局部形变适应能力。网络采用双解码器结构:边缘解码器引入边缘增强路径(EEP)显式捕捉边界信息,精修模糊轮廓;区域解码器采用多层解码器(MLD)利用多尺度深层语义特征,保留细节并精确重建小病灶。此外,在多个尺度上添加辅助深度监督(ADS)头,提供更精准梯度反馈,进一步增强多尺度特征判别力。在三个数据集(NIH Pancreas、MSD、合作医院提供的临床胰腺肿瘤数据集)上进行大量实验,分别获得89.47%、87.59%、89.02%的Dice相似系数,优于多数现有先进方法,在分割精度、边界保持与跨数据集泛化性方面表现优异,验证了方法在真实胰腺CT分割任务中的有效性与通用性。

原文摘要 · Abstract (English)

Accurate segmentation of the pancreas and its lesions in CT scans is crucial for the precise diagnosis and treatment of pancreatic cancer. However, it remains a highly challenging task due to several factors such as low tissue contrast with surrounding organs, blurry anatomical boundaries, irregular organ shapes, and the small size of lesions. To tackle these issues, we propose DB-MSMUNet (Dual-Branch Multi-scale Mamba UNet), a novel encoder-decoder architecture designed specifically for robust pancreatic segmentation. The encoder is constructed using a Multi-scale Mamba Module (MSMM), which combines deformable convolutions and multi-scale state space modeling to enhance both global context modeling and local deformation adaptation. The network employs a dual-decoder design: the edge decoder introduces an Edge Enhancement Path (EEP) to explicitly capture boundary cues and refine fuzzy contours, while the area decoder incorporates a Multi-layer Decoder (MLD) to preserve fine-grained details and accurately reconstruct small lesions by leveraging multi-scale deep semantic features. Furthermore, Auxiliary Deep Supervision (ADS) heads are added at multiple scales to both decoders, providing more accurate gradient feedback and further enhancing the discriminative capability of multi-scale features. We conduct extensive experiments on three datasets: the NIH Pancreas dataset, the MSD dataset, and a clinical pancreatic tumor dataset provided by collaborating hospitals. DB-MSMUNet achieves Dice Similarity Coefficients of 89.47%, 87.59%, and 89.02%, respectively, outperforming most existing state-of-the-art methods in terms of segmentation accuracy, edge preservation, and robustness across different datasets. These results demonstrate the effectiveness and generalizability of the proposed method for real-world pancreatic CT segmentation tasks.

医学图像分割Mamba胰腺

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