提出统一理论框架,让自监督MRI重建方法更可解释、更可靠。
Towards a Unified Theoretical Framework for Splitting-based Self-Supervised MRI Reconstruction
- 构建统一理论框架,揭示自监督风险与监督学习的数学联系。
- 证明自监督方法在理论上等同于加权监督学习,最优预测一致。
- 提供设计新方法的通用空间,适合医学影像与深度学习研究者。
高分辨率、非侵入式磁共振成像(MRI)的需求持续推动技术革新,但长期采集时间仍是主要实际限制。尽管基于深度学习的重建方法实现了加速成像,其主流监督范式依赖难以获取的全采样参考数据。因此,自监督学习(SSL)成为有前景的替代方案,其中分拆方法被广泛采用。然而,大多数现有分拆方法为经验设计,缺乏统一的理论理解。本文提出UNITS(Splitting-based self-supervision统一理论),一个通用的理论框架,用于分拆式自监督MRI重建。理论上,我们证明自监督风险可表示为加权监督风险,因此自监督学习具有与监督学习相同的逐点贝叶斯最优预测器。我们进一步将训练残差与预测偏差关联,揭示不同采样机制对训练行为的影响。UNITS将现有多种方法解释为同一框架下的特例,并通过采样随机性与灵活的数据利用,提供通用的设计空间。这些贡献共同确立了UNITS作为可解释、泛化性强且可应用的自监督MRI重建的理论基础与实践范式。
原文摘要 · Abstract (English)
The demand for high-resolution, non-invasive imaging continues to drive innovation in magnetic resonance imaging (MRI), but long acquisition times remain a major practical limitation. Although deep learning-based reconstruction methods have enabled accelerated imaging, their predominant supervised paradigm relies on fully-sampled reference data that are difficult to acquire in practice. Self-supervised learning (SSL) has therefore emerged as a promising alternative, among which splitting methods are a widely used strategy. However, most existing splitting-based methods are empirically designed, and a unified theoretical understanding remains limited. In this work, we introduce UNITS (Unified Theory for Splitting-based self-supervision), a general theoretical framework for splitting-based self-supervised MRI reconstruction. Theoretically, we show that the self-supervised risk can be expressed as a weighted supervised risk. Consequently, self-supervision admits the same pointwise Bayes-optimal predictor as supervised learning. We further relate the training residual to the prediction bias, revealing how different sampling mechanisms affect training behavior. UNITS makes a broad class of existing methods interpretable as special cases within a common framework, and provides a general design space through sampling stochasticity and flexible data utilization. Together, these contributions establish UNITS as a theoretical foundation, a practical paradigm, and a benchmark for interpretable, generalizable, and applicable self-supervised MRI reconstruction.
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