解决胎儿脑超声成像视角受限问题,提升图像质量与可分析性。
USFetal: Tools for Fetal Brain Ultrasound Compounding
- 系统分类超声融合方法,涵盖经典与深度学习框架
- 在十组多视角数据上验证效果,实现更清晰的脑部结构呈现
- 开源工具箱支持研究复现,适合医学影像与深度学习开发者
超声技术安全、经济且普及,适用于胎儿脑部成像,但存在视角依赖伪影、操作者差异和视野有限等问题,影响解读与定量分析。超声融合通过整合多个3D采集的互补信息,生成统一的体积表示,以克服上述局限。本文提出四项主要贡献:(1) 首次系统化分类胎儿脑超声融合的计算策略,包括传统方法与现代学习型框架;(2) 实现并比较四类代表性方法——多尺度、变换式、变分法与深度学习方法,突出其核心原理与实际优势;(3) 针对监督学习所需的完整视图无伪影真实数据缺乏的问题,聚焦无监督与自监督策略,提出两种新深度学习方法:自监督融合框架与无监督深度插件式先验的适配应用;(4) 在十个多视角胎儿脑超声数据集上进行综合评估,结合放射科专家评分与标准图像质量指标。同时发布USFetal融合工具箱,公开供研究与基准测试使用。
原文摘要 · Abstract (English)
Ultrasound offers a safe, cost-effective, and widely accessible technology for fetal brain imaging, making it especially suitable for routine clinical use. However, it suffers from view-dependent artifacts, operator variability, and a limited field of view, which make interpretation and quantitative evaluation challenging. Ultrasound compounding aims to overcome these limitations by integrating complementary information from multiple 3D acquisitions into a single, coherent volumetric representation. This work provides four main contributions: (1) We present the first systematic categorization of computational strategies for fetal brain ultrasound compounding, including both classical techniques and modern learning-based frameworks. (2) We implement and compare representative methods across four key categories - multi-scale, transformation-based, variational, and deep learning approaches - emphasizing their core principles and practical advantages. (3) Motivated by the lack of full-view, artifact-free ground truth required for supervised learning, we focus on unsupervised and self-supervised strategies and introduce two new deep learning based approaches: a self-supervised compounding framework and an adaptation of unsupervised deep plug-and-play priors for compounding. (4) We conduct a comprehensive evaluation on ten multi-view fetal brain ultrasound datasets, using both expert radiologist scoring and standard quantitative image-quality metrics. We also release the USFetal Compounding Toolbox, publicly available to support benchmarking and future research. Keywords: Ultrasound compounding, fetal brain, deep learning, self-supervised, unsupervised.
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