保护隐私的医院影像持续学习新方法,防止模型遗忘旧病种。
Federated Continual Learning for Privacy-Preserving Hospital Imaging Classification
- 用弹性权重固化+原型记忆,避免更新时遗忘旧任务。
- 每家医院仅存潜在特征原型,不传原始图像。
- 结合差分隐私保护单张影像,适合临床数据安全场景。
放射科深度学习模型依赖多机构数据,但隐私法规和医院间数据分布差异限制了数据集中化。联邦学习(FL)可在不共享原始图像的前提下协同训练,但现有算法通常假设数据分布不变。实际中,医院病例构成、标注规范和设备持续变化,导致模型顺序更新时出现灾难性遗忘。联邦持续学习(FCL)旨在解决此问题,但现有方法或忽视医疗隐私要求,或依赖难以在临床验证的回放缓冲区和公开替代数据集。本文研究在医院作为客户端、接收随时间演化的胸部X光片与标签流的情况下,进行联邦持续学习。提出DP-FedEPC(差分隐私联邦弹性原型融合),将弹性权重固化(EWC)、基于原型的回放机制与客户端差分隐私集成到标准FedAvg框架中。EWC通过约束关键参数更新防止遗忘;潜空间原型记忆保留类别结构,无需存储原始图像;客户端使用差分隐私随机梯度下降(DP-SGD),对截断梯度添加校准高斯噪声,为单张影像提供正式隐私保障。
原文摘要 · Abstract (English)
Deep learning models for radiology interpretation increasingly rely on multi-institutional data, yet privacy regulations and distribution shift across hospitals limit central data pooling. Federated learning (FL) allows hospitals to collaboratively train models without sharing raw images, but current FL algorithms typically assume a static data distribution. In practice, hospitals experience continual evolution in case mix, annotation protocols, and imaging devices, which leads to catastrophic forgetting when models are updated sequentially. Federated continual learning (FCL) aims to reconcile these challenges but existing methods either ignore the stringent privacy constraints of healthcare or rely on replay buffers and public surrogate datasets that are difficult to justify in clinical settings. We study FCL for chest radiography classification in a setting where hospitals are clients that receive temporally evolving streams of cases and labels. We introduce DP-FedEPC (Differentially Private Federated Elastic Prototype Consolidation), a method that combines elastic weight consolidation (EWC), prototype-based rehearsal, and client-side differential privacy within a standard FedAvg framework. EWC constrains updates along parameters deemed important for previous tasks, while a memory of latent prototypes preserves class structure without storing raw images. Differentially private stochastic gradient descent (DP-SGD) at each client adds calibrated Gaussian noise to clipped gradients, providing formal privacy guarantees for individual radiographs.
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