arXiv:2601.07316cs.LGcs.AI2026-01被引 1

将心电图转化为生物对齐的心跳序列,提升诊断准确率与可解释性

BEAT-Net: Injecting Biomimetic Spatio-Temporal Priors for Interpretable ECG Classification

  • 用QRS波段分段将心电图转为生物对齐的心跳序列
  • 仅需30%~35%标注数据即达全监督性能,且鲁棒性强
  • 自动生成临床常用分析习惯,无需额外标注即可解释

尽管深度学习推动了心电图自动诊断的发展,但主流监督方法通常将心电信号视为无差别的一维信号或二维图像,迫使模型隐式学习生理结构,导致数据效率低且缺乏可解释性,与医学推理不符。为此,我们提出BEAT-Net——一种基于分词的心电图语言建模框架。通过QRS波段分词策略,将连续信号转换为生物对齐的心跳序列,架构通过专用编码器显式分解心脏生理:提取局部波形形态、归一化空间导联视角、建模时间节律依赖。在三个大规模基准上的评估表明,BEAT-Net在诊断准确性上媲美主流卷积神经网络(CNN)架构,同时显著提升鲁棒性。该框架展现出极强的数据效率,仅使用30%至35%的标注数据即可恢复全监督性能。此外,学习到的注意力机制能自发重现临床启发式规则,如心律分析中优先关注导联II,无需显式监督。这些结果表明,融入生物先验可提供一种计算高效且可解释的替代方案,避免依赖大规模预训练。

原文摘要 · Abstract (English)

Although deep learning has advanced automated electrocardiogram (ECG) diagnosis, prevalent supervised methods typically treat recordings as undifferentiated one-dimensional (1D) signals or two-dimensional (2D) images. This formulation compels models to learn physiological structures implicitly, resulting in data inefficiency and opacity that diverge from medical reasoning. To address these limitations, we propose BEAT-Net, a Biomimetic ECG Analysis with Tokenization framework that reformulates the problem as a language modeling task. Utilizing a QRS tokenization strategy to transform continuous signals into biologically aligned heartbeat sequences, the architecture explicitly decomposes cardiac physiology through specialized encoders that extract local beat morphology while normalizing spatial lead perspectives and modeling temporal rhythm dependencies. Evaluations across three large-scale benchmarks demonstrate that BEAT-Net matches the diagnostic accuracy of dominant convolutional neural network (CNN) architectures while substantially improving robustness. The framework exhibits exceptional data efficiency, recovering fully supervised performance using only 30 to 35 percent of annotated data. Moreover, learned attention mechanisms provide inherent interpretability by spontaneously reproducing clinical heuristics, such as Lead II prioritization for rhythm analysis, without explicit supervision. These findings indicate that integrating biological priors offers a computationally efficient and interpretable alternative to data-intensive large-scale pre-training.

心电图分析可解释性生物先验数据效率

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