arXiv:2601.07935cs.LGcs.AI2026-01被引 6

用专家混合与低秩适配结合,让大模型学医不丢通用能力。

Towards Specialized Generalists: A Multi-Task MoE-LoRA Framework for Domain-Specific LLM Adaptation

  • 分层部署专家,深层用更多低秩专家捕捉医学语义
  • 在多个医疗任务上超越传统LoRA和MoE,且不遗忘通用知识
  • 适合需要多任务医疗适配又怕灾难性遗忘的场景

大语言模型正从通用能力转向领域专精。但将其适配至医学等专业领域面临两大挑战:一是‘稳定-可塑矛盾’,即学习复杂临床知识时避免遗忘通用世界知识;二是‘任务干扰’,不同子任务如诊断、报告摘要、药物相互作用预测会争抢有限的低秩参数空间。本文提出Med-MoE-LoRA框架,将专家混合(MoE)与低秩适配(LoRA)结合,实现高效多任务领域适配,尤其适用于医疗场景。受最新进展启发,该框架采用非对称专家分布——深层配置更高密度的LoRA专家以捕获复杂语义抽象。同时引入‘知识保护插件’,借鉴LoRA MoE思想,隔离并保护通用推理能力。通过软融合与自适应路由及秩级解耦机制,该方法在医疗基准测试中表现优异,显著降低任务间干扰。实验表明,其在多个临床NLP任务上持续优于标准LoRA与传统MoE架构,同时保持模型通用认知能力。

原文摘要 · Abstract (English)

The rapid evolution of Large Language Models (LLMs) has shifted focus from general-purpose capabilities to domain-specific expertise. However, adapting LLMs to specialized fields such as medicine presents two challenge: (1) the "Stability-Plasticity Dilemma", where the model must acquire complex clinical knowledge without suffering from catastrophic forgetting of general world knowledge; and (2) "Task Interference", where disparate sub-tasks, such as medical diagnosis, report summarization, and drug-drug interaction prediction, compete for limited low-rank parameter space. In this paper, we propose Med-MoE-LoRA, a novel framework that integrates Mixture-of-Experts (MoE) with Low-Rank Adaptation (LoRA) to enable efficient multi-task domain adaptation, especially for medical scenarios. Drawing inspiration from recent advances, our framework employs an asymmetric expert distribution where deeper layers are equipped with a higher density of LoRA experts to capture complex semantic abstractions. We further introduce a "Knowledge-Preservation Plugin", inspired by LoRA MoE, to isolate and protect general-purpose reasoning. By utilizing soft merging with adaptive routing and rank-wise decoupling, Med-MoE-LoRA achieves superior performance in medical benchmarks while reducing interference. Experimental results demonstrate that our approach consistently outperforms standard LoRA and conventional MoE architectures across multiple clinical NLP tasks while retaining the model's general cognitive capabilities.

领域适配专家混合低秩微调医疗AI

Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。