用临床基准提升心率变异性分析,避免AI误判情绪信号。
C-GRASP: Clinically-Grounded Reasoning for Affective Signal Processing
- 构建八步可追溯推理流程,用个体基线替代群体平均值。
- 在DREAMER数据集上实现37.3%情绪分类准确率,临床推理一致性达69.6%。
- 通过自适应呼吸影响防护,防止频域指标被污染,适合医疗AI研究者。
心率变异性(HRV)是自主神经监测的重要无创指标,但将大语言模型(LLM)用于HRV解读时易出现生理幻觉,包括呼吸性窦性心律不齐(RSA)干扰、非线性指标短时数据不稳定,以及忽视个体基线而依赖人群标准。我们提出C-GRASP(临床基础推理用于情感信号处理),一个受约束的RAG增强管道,将HRV解读分解为八个可追踪的推理步骤。核心是Z-score优先级层级,强制以个体基线变化权重高于群体统计。系统通过自动化的RSA感知防护机制,有效缓解频域指标的幻觉问题。在414组来自DREAMER数据集的试验中,结合高规模推理模型(如MedGemma3-thinking)的C-GRASP,在四分类情绪识别中达到37.3%准确率,临床推理一致性(CRC)得分为69.6%。消融实验表明,个体化Delta Z-score模块是关键逻辑锚点,能有效防止原生LLM常见的‘群体偏差’。最终,C-GRASP将情感计算从黑箱分类转向透明、基于证据的临床决策支持,为生物医学工程中的AI安全集成铺平道路。
原文摘要 · Abstract (English)
Heart rate variability (HRV) is a pivotal noninvasive marker for autonomic monitoring; however, applying Large Language Models (LLMs) to HRV interpretation is hindered by physiological hallucinations. These include respiratory sinus arrhythmia (RSA) contamination, short-data instability in nonlinear metrics, and the neglect of individualized baselines in favor of population norms. We propose C-GRASP (Clinically-Grounded Reasoning for Affective Signal Processing), a guardrailed RAG-enhanced pipeline that decomposes HRV interpretation into eight traceable reasoning steps. Central to C-GRASP is a Z-score Priority Hierarchy that enforces the weighting of individualized baseline shifts over normative statistics. The system effectively mitigates spectral hallucinations through automated RSA-aware guardrails, preventing contamination of frequency-domain indices. Evaluated on 414 trials from the DREAMER dataset, C-GRASP integrated with high-scale reasoning models (e.g., MedGemma3-thinking) achieved superior performance in 4-class emotion classification (37.3% accuracy) and a Clinical Reasoning Consistency (CRC) score of 69.6%. Ablation studies confirm that the individualized Delta Z-score module serves as the critical logical anchor, preventing the "population bias" common in native LLMs. Ultimately, C-GRASP transitions affective computing from black-box classification to transparent, evidence-based clinical decision support, paving the way for safer AI integration in biomedical engineering.
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