解决脊椎编号异常的自动识别与标注,提升影像诊断准确性。
VERIDAH: Solving Enumeration Anomaly Aware Vertebra Labeling across Imaging Sequences
- 采用多分类头与加权序列预测结合的方法,自动识别异常脊椎数量。
- 在T2w和CT图像上正确标注全部脊椎的准确率分别达98.30%和99.18%。
- 适用于任意视野范围图像,适合临床影像分析与手术规划使用。
人类脊柱通常由7个颈椎、12个胸椎和5个腰椎组成,但存在编号异常的情况,如胸椎为11或13个,腰椎为4或6个。尽管此类异常对慢性背痛和手术规划具有潜在临床意义,但胸腰交界区常被忽略且少有报告提及。现有基于深度学习的脊椎标注方法缺乏对异常情况的处理能力。本文提出「带异常处理的脊椎识别」(VERIDAH),一种基于多分类头与加权脊椎序列预测算法的新方法。实验表明,该方法在T2w TSE矢状位图像上正确标注所有脊椎的比例达到98.30%,显著优于现有模型(94.24%,p < 0.001);在CT图像上达到99.18%,远超对比模型的77.26%(p < 0.001)。VERIDAH在T2w和CT图像中分别以87.80%和96.30%的准确率识别胸椎异常,腰椎异常识别准确率分别为94.48%和97.22%。该方法适用于任意视野图像,代码与模型已开源:https://github.com/Hendrik-code/spineps。
原文摘要 · Abstract (English)
The human spine commonly consists of seven cervical, twelve thoracic, and five lumbar vertebrae. However, enumeration anomalies may result in individuals having eleven or thirteen thoracic vertebrae and four or six lumbar vertebrae. Although the identification of enumeration anomalies has potential clinical implications for chronic back pain and operation planning, the thoracolumbar junction is often poorly assessed and rarely described in clinical reports. Additionally, even though multiple deep-learning-based vertebra labeling algorithms exist, there is a lack of methods to automatically label enumeration anomalies. Our work closes that gap by introducing "Vertebra Identification with Anomaly Handling" (VERIDAH), a novel vertebra labeling algorithm based on multiple classification heads combined with a weighted vertebra sequence prediction algorithm. We show that our approach surpasses existing models on T2w TSE sagittal (98.30% vs. 94.24% of subjects with all vertebrae correctly labeled, p < 0.001) and CT imaging (99.18% vs. 77.26% of subjects with all vertebrae correctly labeled, p < 0.001) and works in arbitrary field-of-view images. VERIDAH correctly labeled the presence 2 Möller et al. of thoracic enumeration anomalies in 87.80% and 96.30% of T2w and CT images, respectively, and lumbar enumeration anomalies in 94.48% and 97.22% for T2w and CT, respectively. Our code and models are available at: https://github.com/Hendrik-code/spineps.
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