arXiv:2601.15235cs.CVcs.AI2026-01被引 1

用2D投影生成椎体轮廓,实现颈椎骨折精准识别。

Tracing 3D Anatomy in 2D Strokes: A Multi-Stage Projection Driven Approach to Cervical Spine Fracture Identification

  • 从多视角投影中定位颈椎,通过2D图像估算椎体掩码。
  • 2D掩码反投影融合后,骨折分类准确率达82.26%(患者级F1)。
  • 方法更高效且可解释,适合临床辅助诊断场景。

颈椎骨折需快速准确诊断,但自动CT解读仍具挑战,因细微损伤需在大范围3D体积中评估。本文探讨全3D椎体分割是否为自动骨折识别所必需,或仅通过2D投影近似即可保留足够诊断信息。提出端到端流程:先用YOLOv8在多视角方差投影中定位脊柱感兴趣区域,3D mIoU达94.45%;再基于能量型矢状与冠状投影,采用DenseNet121-Unet进行多标签椎体分割,平均Dice分数为87.86%;随后将预测的2D掩码反投影并融合,生成各椎体近似3D掩码,提取原始CT中的感兴趣体积;最后由2.5D时空卷积-注意力模型集成分析,获得椎体级与患者级F1分数分别为68.15和82.26,ROC-AUC为91.62和90.95,PR-AUC为75.60和92.00。投影衍生体积在骨折识别性能上媲美全3D分割基线,同时将椎体分割置于低维空间。显著性可解释性与观察者间变异性分析验证了模型的可靠性与可解释性。结果表明,投影驱动的掩码近似是颈椎骨折识别中全3D分割的有效替代方案。

原文摘要 · Abstract (English)

Cervical spine fractures require rapid and accurate diagnosis, yet automatic CT interpretation remains challenging as subtle injuries must be assessed across large 3D volumes. We ask whether full 3D vertebra segmentation is necessary for automated fracture recognition, or whether vertebra masks approximated from 2D projections can preserve sufficient diagnostic context. We propose an end-to-end pipeline that localizes the cervical spine, estimates C1-C7 vertebra masks from optimized 2D projections, and uses the resulting vertebra-level volumes for downstream fracture classification. A YOLOv8 detector first localizes spine regions of interest from multi-view variance projections, achieving a 3D mean Intersection over Union of 94.45%. Multi-label vertebra segmentation is then performed with a DenseNet121-Unet on energy-based sagittal and coronal projections, attaining a mean Dice score of 87.86%. The predicted 2D masks are back-projected and fused into approximate 3D masks for each vertebra to extract volumes of interest from the original CT. These volumes are analyzed by an ensemble of 2.5D spatio-sequential CNN-Transformer models, yielding vertebra-level and patient-level F1 scores of 68.15 and 82.26, area under the receiver operating characteristic curve of 91.62 and 90.95, and area under the precision-recall curve of 75.60 and 92.00, respectively. The projection-derived volumes achieved fracture-recognition performance comparable to a full 3D-segmentation baseline, while shifting the vertebra segmentation stage into a lower-dimensional domain. Saliency-based explainability and interobserver variability analysis further examine interpretability and reliability. Overall, the results indicate that projection-based mask approximation is a viable proxy for full 3D vertebra segmentation in cervical fracture recognition.

医学影像骨折检测2D投影可解释性

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