arXiv:2601.16302cs.CV2026-01

通过联合学习模板与任务,提升多机构医学影像联邦学习的性能。

FeTTL: Federated Template and Task Learning for Multi-Institutional Medical Imaging

  • 构建全局模板与任务模型联合优化框架,对齐多中心数据分布。
  • 在视网膜和病理图像任务上显著优于现有联邦学习方法(p<0.002)。
  • 适合需要跨机构协作且数据异构的医疗影像研究者使用。

联邦学习可在保护数据隐私的前提下实现跨地理分布的医疗中心协同建模,但数据域偏移和异质性常导致模型性能下降。医学影像尤其受成像协议、扫描设备和患者群体差异的影响。为此,我们提出联邦模板与任务学习(FeTTL),一种专为联邦环境中多机构医学影像数据调和设计的新框架。FeTTL联合学习全局模板与任务模型,以对齐各客户端的数据分布。我们在两个具有挑战性和多样性的多机构医学影像任务上评估了该方法:视网膜眼底视盘分割和组织病理学转移灶分类。实验结果表明,FeTTL在上述两项任务中均显著优于当前最先进的联邦学习基线(p-values < 0.002)。实验还强调了模板与任务联合学习的重要性。这些发现表明,FeTTL为缓解联邦学习中的分布偏移提供了原则性且可扩展的解决方案,支持在真实多机构环境中实现稳健的模型部署。

原文摘要 · Abstract (English)

Federated learning enables collaborative model training across geographically distributed medical centers while preserving data privacy. However, domain shifts and heterogeneity in data often lead to a degradation in model performance. Medical imaging applications are particularly affected by variations in acquisition protocols, scanner types, and patient populations. To address these issues, we introduce Federated Template and Task Learning (FeTTL), a novel framework designed to harmonize multi-institutional medical imaging data in federated environments. FeTTL learns a global template together with a task model to align data distributions among clients. We evaluated FeTTL on two challenging and diverse multi-institutional medical imaging tasks: retinal fundus optical disc segmentation and histopathological metastasis classification. Experimental results show that FeTTL significantly outperforms the state-of-the-art federated learning baselines (p-values <0.002) for optical disc segmentation and classification of metastases from multi-institutional data. Our experiments further highlight the importance of jointly learning the template and the task. These findings suggest that FeTTL offers a principled and extensible solution for mitigating distribution shifts in federated learning, supporting robust model deployment in real-world, multi-institutional environments.

联邦学习医学影像数据对齐

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