arXiv:2601.17143eess.IVphysics.med-ph2026-01被引 1

用分阶段训练和隐式插值,实现3D磁共振指纹成像的快速高精度重建。

Fully 3D Unrolled Magnetic Resonance Fingerprinting Reconstruction via Staged Pretraining and Implicit Gridding

  • 采用分阶段训练+隐式网格化,高效融合数据一致性约束
  • 1毫米各向同性分辨率下,重建质量优于传统方法,2分钟扫描提速111倍
  • 30秒扫描即可达到2分钟扫描的T1图准确度,适合临床加速成像

磁共振指纹成像(MRF)可实现快速定量成像,但高分辨率3D重建仍计算耗时。非笛卡尔重建需重复非均匀FFT,常用局部低秩(LLR)先验带来额外开销且在高加速下失效。学习型3D先验可缓解此问题,但大规模训练受内存与时间限制。本文提出SPUR-iG,一种全3D深度展开子空间重建框架,结合高效数据一致性和渐进式训练策略。数据一致性利用隐式GROG,通过隐式学习核函数将非笛卡尔数据映射到笛卡尔网格,支持基于FFT的更新并最小化伪影。训练分为三阶段:(1) 广泛数据增强预训练去噪器,(2) 迭代贪心展开训练,(3) 梯度检查点微调。三阶段协同使大规模3D展开学习在合理算力内可行。在大规模体内数据集上,回顾性欠采样测试表明,相比LLR和混合2D/3D展开基线,SPUR-iG在1毫米各向同性分辨率下显著提升子空间系数图质量和定量准确性。全脑重建时间低于15秒,2分钟采集最多提速111倍。值得注意的是,30秒扫描获得的T1图准确度与2分钟扫描的LLR重建相当或更优。整体框架提升了大尺度3D MRF重建的精度与速度,支持高效可靠的加速定量成像。

原文摘要 · Abstract (English)

Magnetic Resonance Fingerprinting (MRF) enables fast quantitative imaging, yet reconstructing high-resolution 3D data remains computationally demanding. Non-Cartesian reconstructions require repeated non-uniform FFTs, and the commonly used Locally Low Rank (LLR) prior adds computational overhead and becomes insufficient at high accelerations. Learned 3D priors could address these limitations, but training them at scale is challenging due to memory and runtime demands. We propose SPUR-iG, a fully 3D deep unrolled subspace reconstruction framework that integrates efficient data consistency with a progressive training strategy. Data consistency leverages implicit GROG, which grids non-Cartesian data onto a Cartesian grid with an implicitly learned kernel, enabling FFT-based updates with minimal artifacts. Training proceeds in three stages: (1) pretraining a denoiser with extensive data augmentation, (2) greedy per-iteration unrolled training, and (3) final fine-tuning with gradient checkpointing. Together, these stages make large-scale 3D unrolled learning feasible within a reasonable compute budget. On a large in vivo dataset with retrospective undersampling, SPUR-iG improves subspace coefficient maps quality and quantitative accuracy at 1-mm isotropic resolution compared with LLR and a hybrid 2D/3D unrolled baseline. Whole-brain reconstructions complete in under 15-seconds, with up to $\times$111 speedup for 2-minute acquisitions. Notably, $T_1$ maps with our method from 30-second scans achieve accuracy on par with or exceeding LLR reconstructions from 2-minute scans. Overall, the framework improves both accuracy and speed in large-scale 3D MRF reconstruction, enabling efficient and reliable accelerated quantitative imaging.

MRI重建深度学习加速成像3D重建

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