用物理约束神经网络，仅凭流量数据就能精准估算液体分离器中的液层高度。

Separating liquid-liquid dispersions in gravity settlers is critical in chemical, pharmaceutical, and recycling processes. The dense-packed zone height is an important performance and safety indicator but it is often expensive and impractical to measure due to optical limitations. We propose a framework to estimate phase heights by combining a PINN model with readily available volume flow measurements, without requiring phase height measurements during deployment. To this end, a physics-informed neural network (PINN) is first pretrained on synthetic data and physics equations derived from a low-fidelity (approximate) mechanistic model to reduce the need for extensive experimental data. While the mechanistic model is used to generate synthetic training data, only volume balance equations are used in the PINN, as incorporating droplet coalescence and sedimentation submodels would be computationally prohibitive. The pretrained PINN is then fine-tuned with scarce experimental phase height and flow-rate data to capture the actual dynamics of the separator. We then deploy the differentiable PINN as a predictive model in an Extended Kalman Filter inspired state estimation framework, enabling the phase heights to be tracked and updated using flow-rate measurements only. We first test the two-stage trained PINN by forward simulation from a known initial state against the mechanistic model and a non-pretrained PINN. We then evaluate phase height estimation performance with the filter, comparing the two-stage trained PINN with a two-stage trained purely data-driven neural network. All model types are trained and evaluated using ensembles to account for model parameter uncertainty. In all evaluations, the two-stage trained PINN yields the most accurate phase-height estimates.