SimTO自动生成适配复杂物体的软机械手，无需人工设定受力条件。

Soft robotic grippers are essential for grasping delicate, geometrically complex objects in manufacturing, healthcare and agriculture. However, existing designs struggle to grasp feature-rich objects with high topological variability, including gears with sharp tooth profiles on automotive assembly lines, corals with fragile protrusions, or vegetables with irregular branching structures like broccoli. Unlike simple geometric primitives such as cubes or spheres, feature-rich objects lack a clear "optimal" contact surface, making them both difficult to grasp and susceptible to damage. Safe handling of such objects therefore requires specialized soft grippers whose morphology is tailored to the object's features. Topology optimization offers a promising approach for producing specialized grippers, but its utility is limited by the need for pre-defined load cases. For soft grippers, these loads arise from hundreds of unpredictable gripper-object contact forces during grasping and are unknown a priori. To address this problem, we introduce SimTO, a two-stage, simulation-driven topology optimization framework that automatically extracts load cases from a dynamic, contact-rich grasping simulation before performing classical topology optimization, eliminating the need for manual load specification. Given an arbitrary feature-rich object, SimTO produces highly customized soft grippers with fine-grained morphological features tailored to the object geometry. Physical experiments confirm that our specialized grippers achieve higher grasp forces than a generalist design produced by conventional topology optimization methods, while numerical experiments show that they achieve high grasp success rates across varying object poses and strong generalization to a set of unseen objects.