让自动驾驶更懂罕见危险场景，提升复杂路况下的安全决策能力。

End-to-end autonomous driving models increasingly benefit from large vision--language models for semantic understanding, yet ensuring safe and accurate operation under long-tail conditions remains challenging. These challenges are particularly prominent in long-tail mixed-traffic scenarios, where autonomous vehicles must interact with heterogeneous road users, including human-driven vehicles and vulnerable road users, under complex and uncertain conditions. This paper proposes HERMES, a holistic risk-aware end-to-end multimodal driving framework designed to inject explicit long-tail risk cues into trajectory planning. HERMES employs a foundation-model-assisted annotation pipeline to produce structured Long-Tail Scene Context and Long-Tail Planning Context, capturing hazard-centric cues together with maneuver intent and safety preference, and uses these signals to guide end-to-end planning. HERMES further introduces a Tri-Modal Driving Module that fuses multi-view perception, historical motion cues, and semantic guidance, ensuring risk-aware accurate trajectory planning under long-tail scenarios. Experiments on the real-world long-tail dataset demonstrate that HERMES consistently outperforms representative end-to-end and VLM-driven baselines under long-tail mixed-traffic scenarios. Ablation studies verify the complementary contributions of key components.