arXiv:2602.01086cs.AIcs.CR2026-02

用不可变数据结构构建可追溯的临床信息图谱,提升医疗AI推理的可信度。

MedBeads: An AI-Native Clinical Context Graph Built from Immutable Beads and Reconstructable Clinical Links

  • 将临床记录封装为不可变的Bead,通过哈希与默克尔有向无环图组织
  • 基于签名规则重建临床关联,支持知识更新而不修改原始数据
  • 适用于需审计、可复现的医疗AI系统,如临床决策支持

生成式AI虽蕴含大量医学知识,但患者特定回答受限于推理时提供的上下文。电子健康记录和FHIR支持文档与互操作性,却无法自动定义完整、实时且可审计的模型输入上下文。基于相似性的检索虽能定位相关文本,但既不能保证获取临床相关的记录,也无法显式揭示遗漏。本文提出MedBeads,一种面向AI的临床记录基础架构,在生成前构建纵向患者信息的声明闭包。每个Bead是通过内容哈希(SHA-256)标识的不可变临床或知识对象,以患者专属Pod中追加只读形式存储。结构父边构成以患者为根的默克尔有向无环图(Merkle DAG)。类型化临床链接位于独立的可重建解释层,由已签名、版本化的知识规则推导而来;当知识变更时可重新计算,无需重写临床事实。检索遵循授权的结构与临床边,处理修订与撤回,并报告策略限制或令牌截断。开源Go实现使用追加只读Pod与可重建SQLite投影。对1,135个合成Synthea FHIR包进行文件转换,生成约一百万个Bead,验证了临床链接推导与解释层重建的确定性。这些工程结果证明可行性与可复现性,但不意味着减少幻觉或改善临床结果。MedBeads将问题重构为数据结构问题,提供政策约束、带溯源的临床子图,而非模糊的相似片段列表。

原文摘要 · Abstract (English)

Generative AI can encode substantial medical knowledge, but patient-specific answers remain constrained by the context supplied at inference time. Electronic health records and FHIR support documentation and interoperability, but they do not by themselves define the complete, current, and auditable context a model should receive. Similarity-based retrieval can find related text, but it neither guarantees collection of clinically connected records nor makes omissions explicit. We introduce MedBeads, an AI-facing clinical record substrate that assembles a declared closure of longitudinal patient information before generation. A Bead is an immutable clinical or knowledge object identified by SHA-256 over canonical content and stored as an append-only frame in a patient-scoped Pod. Structural parent edges form a patient-rooted Merkle DAG. Typed clinical links occupy a separate, reconstructable interpretation layer derived from signed, versioned knowledge rules; they can be recomputed when knowledge changes without rewriting clinical facts. Retrieval follows authorized structural and clinical edges, resolves amendments and retractions, and reports policy or token truncation. An open-source Go implementation uses append-only Pods and reconstructable SQLite projections. File-based conversion of 1,135 synthetic Synthea FHIR bundles produced approximately one million Beads and demonstrated deterministic clinical-link derivation and interpretation-layer reconstruction. These engineering results establish feasibility and reproducibility, not reduced hallucination or improved clinical outcomes. MedBeads reframes grounding as a data-structure problem by delivering a policy-bounded, provenance-bearing clinical subgraph rather than an opaque list of similar fragments.

医疗AI临床图谱数据结构可追溯性

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