arXiv:2602.07979cs.CV2026-02

用多能谱先验增强的双域扩散模型,提升超低剂量光子计数CT图像质量。

FSP-Diff: Full-Spectrum Prior-Enhanced DualDomain Latent Diffusion for Ultra-Low-Dose Spectral CT Reconstruction

  • 融合投影域去噪与图像域重建,平衡细节保留与噪声抑制。
  • 通过全谱图像建立统一结构参考,跨能谱协同优化重建结果。
  • 在低维潜空间中加速扩散生成,兼顾高保真度与计算效率。

基于光子计数探测器的光谱计算机断层扫描(CT)在组织表征和物质区分方面具有巨大潜力。然而,在超低剂量条件下,各能谱投影的信噪比急剧下降,导致重建图像出现严重伪影并丢失结构细节。为此,本文提出FSP-Diff:一种全谱先验增强的双域潜空间扩散框架,用于超低剂量光谱CT重建。该框架包含三项核心策略:1)互补特征构建:融合直接图像重建与投影域去噪结果,前者保留噪声中的纹理信息,后者提供稳定结构支撑;2)全谱先验整合:将多能谱投影融合为高信噪比全谱图像,作为跨能谱重建的统一结构参考;3)高效潜空间扩散合成:通过多路径特征嵌入紧凑潜空间,降低高维数据计算开销,实现低维流形上的交互特征融合,显著提升重建速度并保持细粒度恢复能力。在模拟与真实数据集上的大量实验表明,FSP-Diff在图像质量与计算效率上均显著优于现有先进方法,展现出临床可行的超低剂量光谱CT成像潜力。

原文摘要 · Abstract (English)

Spectral computed tomography (CT) with photon-counting detectors holds immense potential for material discrimination and tissue characterization. However, under ultra-low-dose conditions, the sharply degraded signal-to-noise ratio (SNR) in energy-specific projections poses a significant challenge, leading to severe artifacts and loss of structural details in reconstructed images. To address this, we propose FSP-Diff, a full-spectrum prior-enhanced dual-domain latent diffusion framework for ultra-low-dose spectral CT reconstruction. Our framework integrates three core strategies: 1) Complementary Feature Construction: We integrate direct image reconstructions with projection-domain denoised results. While the former preserves latent textural nuances amidst heavy noise, the latter provides a stable structural scaffold to balance detail fidelity and noise suppression. 2) Full-Spectrum Prior Integration: By fusing multi-energy projections into a high-SNR full-spectrum image, we establish a unified structural reference that guides the reconstruction across all energy bins. 3) Efficient Latent Diffusion Synthesis: To alleviate the high computational burden of high-dimensional spectral data, multi-path features are embedded into a compact latent space. This allows the diffusion process to facilitate interactive feature fusion in a lower-dimensional manifold, achieving accelerated reconstruction while maintaining fine-grained detail restoration. Extensive experiments on simulated and real-world datasets demonstrate that FSP-Diff significantly outperforms state-of-the-art methods in both image quality and computational efficiency, underscoring its potential for clinically viable ultra-low-dose spectral CT imaging.

光谱CT扩散模型超低剂量双域重建

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