arXiv:2602.11957cs.LG2026-02

用双模型架构提升医药内容合规性检测,误检率降5倍

Are Two LLMs Better Than One? A Student-Teacher Dual-Head LLMs Architecture for Pharmaceutical Content Optimization

  • 采用学生-教师双模型+人工审核流水线,实现可验证的内容质检
  • 在AIReg-Bench上达83.0%准确率,漏检减少5倍,错字识别率达92.5%
  • 适合医药、金融等强监管领域快速部署,支持透明可解释的质检流程

大语言模型(LLM)在医药等受监管领域的内容生成中日益重要,但输出需兼具科学准确性与法律合规性。人工质检效率低且易出错,易成出版瓶颈。本文提出LRBTC,一种基于模块化LLM与视觉语言模型(VLM)的质检架构,涵盖语言、法规、品牌、技术及内容结构五类检查。该架构结合学生-教师双模型机制、人机协同(HITL)工作流与瀑布式规则过滤,实现可扩展、可验证的内容验证与优化。在AIReg-Bench上,方法达到83.0% F1值和97.5%召回率,相比Gemini 2.5 Pro漏检减少5倍;在CSpelling数据集上,平均准确率提升26.7%。错误分析显示,当前模型对拼写错误识别能力强(92.5%召回),但对复杂医学语法(25.0%召回)和标点错误(41.7%召回)仍表现不佳,提示未来改进方向。本研究提供了一套即插即用的可靠、透明的高风险行业内容质检方案,并开放Demo供MIT许可使用。

原文摘要 · Abstract (English)

Large language models (LLMs) are increasingly used to create content in regulated domains such as pharmaceuticals, where outputs must be scientifically accurate and legally compliant. Manual quality control (QC) is slow, error prone, and can become a publication bottleneck. We introduce LRBTC, a modular LLM and vision language model (VLM) driven QC architecture covering Language, Regulatory, Brand, Technical, and Content Structure checks. LRBTC combines a Student-Teacher dual model architecture, human in the loop (HITL) workflow with waterfall rule filtering to enable scalable, verifiable content validation and optimization. On AIReg-Bench, our approach achieves 83.0% F1 and 97.5% recall, reducing missed violations by 5x compared with Gemini 2.5 Pro. On CSpelling, it improves mean accuracy by 26.7%. Error analysis further reveals that while current models are strong at detecting misspellings (92.5 recall), they fail to identify complex medical grammatical (25.0 recall) and punctuation (41.7 recall) errors, highlighting a key area for future work. This work provides a practical, plug and play solution for reliable, transparent quality control of content in high stakes, compliance critical industries. We also provide access to our Demo under MIT Licenses.

LLM质检医药AI双模型合规检测

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