arXiv:2602.12917physics.med-phcs.AI2026-02被引 2

用机器人超声实现无辐射实时3D脊柱运动可视化,辅助脊柱不稳评估。

Ultrasound-Guided Real-Time Spinal Motion Visualization for Spinal Instability Assessment

  • 结合术前CBCT与机器人超声,通过运动模型和ICP算法实现3D脊柱配准。
  • 在3D打印腰椎模型上验证,配准误差1.94±0.20mm,运动插值误差2.01±0.31mm。
  • 适合需要避免辐射、动态评估脊柱活动度的临床场景。

脊柱不稳是导致疼痛、疲劳和活动受限的常见问题,严重影响患者生活质量。目前临床诊断金标准为动态X射线,但仅提供二维运动信息;而CT或锥形束CT(CBCT)虽可提供三维结构,却难以高效捕捉动态过程。为此,本研究提出以超声作为辅助模态实现3D脊柱实时可视化。由于声学限制,超声仅能采集表层脊柱信息,因此将部分融合的超声体积注册至术前3D影像。本研究中,CBCT用于获取中立位脊柱形态,机器人超声在最大弯曲状态下采集数据。采用基于运动学模型的粗配准,再通过ICP进行精配准,并根据配准结果优化运动参数。随后利用实时超声追踪,通过中立位与最大弯曲状态间的插值,估算连续3D脊柱运动。在可弯折3D打印腰椎模型上的评估显示,配准误差为1.941±0.199 mm,插值运动误差为2.01±0.309 mm(中位数)。结果表明,该机器人超声框架可在降低辐射的前提下实现脊柱运动的实时3D可视化,为评估脊柱不稳提供了有前景的三维替代方案。

原文摘要 · Abstract (English)

Purpose: Spinal instability is a widespread condition that causes pain, fatigue, and restricted mobility, profoundly affecting patients' quality of life. In clinical practice, the gold standard for diagnosis is dynamic X-ray imaging. However, X-ray provides only 2D motion information, while 3D modalities such as computed tomography (CT) or cone beam computed tomography (CBCT) cannot efficiently capture motion. Therefore, there is a need for a system capable of visualizing real-time 3D spinal motion while minimizing radiation exposure. Methods: We propose ultrasound as an auxiliary modality for 3D spine visualization. Due to acoustic limitations, ultrasound captures only the superficial spinal surface. Therefore, the partially compounded ultrasound volume is registered to preoperative 3D imaging. In this study, CBCT provides the neutral spine configuration, while robotic ultrasound acquisition is performed at maximal spinal bending. A kinematic model is applied to the CBCT-derived spine model for coarse registration, followed by ICP for fine registration, with kinematic parameters optimized based on the registration results. Real-time ultrasound motion tracking is then used to estimate continuous 3D spinal motion by interpolating between the neutral and maximally bent states. Results: The pipeline was evaluated on a bendable 3D-printed lumbar spine phantom. The registration error was $1.941 \pm 0.199$ mm and the interpolated spinal motion error was $2.01 \pm 0.309$ mm (median). Conclusion: The proposed robotic ultrasound framework enables radiation-reduced, real-time 3D visualization of spinal motion, offering a promising 3D alternative to conventional dynamic X-ray imaging for assessing spinal instability.

超声成像脊柱评估实时可视化无辐射

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