arXiv:2602.14641quant-phcs.LG2026-02

用中性原子量子系统提升小规模医学数据的预测稳定性与准确率

Quantum Reservoir Computing with Neutral Atoms on a Small, Complex, Medical Dataset

  • 采用中性原子量子储层计算,通过硬件执行生成新特征
  • 硬件运行比模拟更稳定,测试准确率显著提升,平均达85.3%
  • 适合处理小样本、高相关性医学数据,对医疗预测有潜力

基于生物标志物的临床结局预测因非线性关系、特征相关性及数据集规模有限而具有挑战性。传统机器学习方法在此类条件下表现不佳,促使探索替代方案。本文研究了量子储层计算(QRC),在无噪声模拟和中性原子里德堡处理器Aquila上进行硬件执行。对比六种经典模型,使用SHAP生成特征子集。结果显示,基于模拟量子特征训练的模型平均测试准确率与经典特征相当,但训练准确率更高且在不同数据划分间波动更大,表明存在过拟合。而在硬件执行与无噪声模拟的对比中,模型对数据划分更具鲁棒性,平均测试准确率常有统计学意义的提升。这种准确率提升与稳定性增强的组合,暗示硬件执行可能具有正则化效应。进一步分析发现,硬件执行产生的量子特征分布具有结构化的时变变换特性:向均值压缩,互信息逐步降低,相较模拟更具抑制过拟合的倾向。

原文摘要 · Abstract (English)

Biomarker-based prediction of clinical outcomes is challenging due to nonlinear relationships, correlated features, and the limited size of many medical datasets. Classical machine-learning methods can struggle under these conditions, motivating the search for alternatives. In this work, we investigate quantum reservoir computing (QRC), using both noiseless emulation and hardware execution on the neutral-atom Rydberg processor \textit{Aquila}. We evaluate performance with six classical machine-learning models and use SHAP to generate feature subsets. We find that models trained on emulated quantum features achieve mean test accuracies comparable to those trained on classical features, but have higher training accuracies and greater variability over data splits, consistent with overfitting. When comparing hardware execution of QRC to noiseless emulation, the models are more robust over different data splits and often exhibit statistically significant improvements in mean test accuracy. This combination of improved accuracy and increased stability is suggestive of a regularising effect induced by hardware execution. To investigate the origin of this behaviour, we examine the statistical differences between hardware and emulated quantum feature distributions. We find that hardware execution applies a structured, time-dependent transformation characterised by compression toward the mean and a progressive reduction in mutual information relative to emulation.

量子计算医疗预测储层计算小样本

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