arXiv:2602.15304cs.LGcs.AI2026-02被引 1

混合联邦与分割学习,实现医疗决策建模的隐私保护。

Hybrid Federated and Split Learning for Privacy Preserving Clinical Prediction and Treatment Optimization

  • 结合联邦与分割学习,在不共享原始数据前提下训练模型。
  • 在非独立同分布数据下仍保持良好预测性能与排序能力。
  • 支持可调的隐私-效用权衡,适合实际医疗系统部署。

临床决策支持常受治理与隐私规则限制,无法跨机构共享患者级数据。本文提出一种混合隐私保护框架,融合联邦学习(FL)与分割学习(SL),在不共享原始数据的情况下支持面向决策的医疗建模。该方法将特征提取模块保留在客户端,预测头部署于协调服务器,实现共享表示学习,并在切层处设置明确的协作边界以实施隐私控制。我们通过成员推理攻击实证评估泄漏风险,并研究基于激活截断与加性高斯噪声的轻量级防御机制。在三个公开临床数据集上,采用统一流程评估,覆盖四类关键维度:实际预测性能、容量受限下的提升排名、审计隐私泄漏和通信开销。结果表明,混合 FL-SL 变体在预测性能与决策导向排序方面优于独立使用 FL 或 SL,且可通过配置实现可调的隐私-效用平衡,显著降低审计泄漏风险,无需共享原始数据。整体上,该工作确立了混合 FL-SL 作为隐私保护医疗决策支持的实用设计空间。

原文摘要 · Abstract (English)

Collaborative clinical decision support is often constrained by governance and privacy rules that prevent pooling patient-level records across institutions. We present a hybrid privacy-preserving framework that combines Federated Learning (FL) and Split Learning (SL) to support decision-oriented healthcare modeling without raw-data sharing. The approach keeps feature-extraction trunks on clients while hosting prediction heads on a coordinating server, enabling shared representation learning and exposing an explicit collaboration boundary where privacy controls can be applied. Rather than assuming distributed training is inherently private, we audit leakage empirically using membership inference on cut-layer representations and study lightweight defenses based on activation clipping and additive Gaussian noise. We evaluate across three public clinical datasets under non-IID client partitions using a unified pipeline and assess performance jointly along four deployment-relevant axes: factual predictive utility, uplift-based ranking under capacity constraints, audited privacy leakage, and communication overhead. Results show that hybrid FL-SL variants achieve competitive predictive performance and decision-facing prioritization behavior relative to standalone FL or SL, while providing a tunable privacy-utility trade-off that can reduce audited leakage without requiring raw-data sharing. Overall, the work positions hybrid FL-SL as a practical design space for privacy-preserving healthcare decision support where utility, leakage risk, and deployment cost must be balanced explicitly.

隐私计算医疗AI联邦学习分割学习

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