arXiv:2602.22367cs.LGcs.AI2026-02被引 1

用几何感知模型高效模拟心电图,仅需少量解剖数据即可保持高精度。

Learning geometry-dependent lead-field operators for forward ECG modeling

  • 构建几何编码与神经代理结合的替代模型,降低计算成本。
  • 心内心外平均角度误差5°,心电图相对均方误差小于2.5%。
  • 适合临床数据有限场景,无需完整躯干分割,易部署于实际应用。

现代心电图正向计算模型依赖于精确的躯干几何表示。导联场方法可在保留完整几何细节的同时实现快速仿真,但在临床实践中,由于成像通常聚焦心脏且常不包含完整躯干,获取高解剖精度仍具挑战性。此外,导联场方法的计算成本随电极数量线性增长,限制了其在高密度记录中的应用。目前尚无方法能同时满足高解剖保真度、低数据需求和计算高效。本文提出一种形状感知的导联场算子代理模型,可直接替代全阶模型进行正向心电图仿真。该框架包含两个部分:几何编码模块将解剖形态映射至低维潜在空间;几何条件神经代理从空间坐标、电极位置和潜在码中预测导联场梯度。所提方法在躯干内部(平均角度误差5°)和心脏内部均实现高精度导联场逼近,心电图仿真相对均方误差低于2.5%。代理模型始终优于广泛使用的伪导联场近似,且推理开销可忽略。得益于紧凑的潜在表示,该方法无需完整躯干分割,可在数据受限环境下部署,同时保持高保真心电图仿真。

原文摘要 · Abstract (English)

Modern forward electrocardiogram (ECG) computational models rely on an accurate representation of the torso domain. The lead-field method enables fast ECG simulations while preserving full geometric fidelity. Achieving high anatomical accuracy in torso representation is, however, challenging in clinical practice, as imaging protocols are typically focused on the heart and often do not include the entire torso. In addition, the computational cost of the lead-field method scales linearly with the number of electrodes, limiting its applicability in high-density recording settings. To date, no existing approach simultaneously achieves high anatomical fidelity, low data requirements and computational efficiency. In this work, we propose a shape-informed surrogate model of the lead-field operator that serves as a drop-in replacement for the full-order model in forward ECG simulations. The proposed framework consists of two components: a geometry-encoding module that maps anatomical shapes into a low-dimensional latent space, and a geometry-conditioned neural surrogate that predicts lead-field gradients from spatial coordinates, electrode positions and latent codes. The proposed method achieves high accuracy in approximating lead fields both within the torso (mean angular error 5°) and inside the heart, resulting in highly accurate ECG simulations (relative mean squared error <2.5%. The surrogate consistently outperforms the widely used pseudo lead-field approximation while preserving negligible inference cost. Owing to its compact latent representation, the method does not require a fully detailed torso segmentation and can therefore be deployed in data-limited settings while preserving high-fidelity ECG simulations.

心电图建模几何学习代理模型低数据

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