用自相似先验与连续时间动态优化足部溃疡分割边界,提升精度与可解释性。
Explainable Continuous-Time Mask Refinement with Local Self-Similarity Priors for Medical Image Segmentation
- 引入局部自相似机制提取光照不变纹理特征,分离坏死组织与背景。
- 通过液态时间常数模块将边界演化建模为微分方程,连续迭代优化分割结果。
- 模型参数仅2570万,边界精度达86.96% Dice和8.91像素HD95,适合移动医疗场景。
准确的足部溃疡语义分割对自动化伤口监测至关重要,但组织异质性和与周围皮肤低对比度导致边界划分困难。为克服传统基于强度网络的局限,我们提出LSS-LTCNet:一种前处理可解释框架,融合确定性结构先验与连续时间神经动力学。其架构摒弃传统黑箱模型,采用局部自相似(LSS)机制提取密集、光照不变的纹理描述子,显式区分坏死组织与背景伪影。为强化拓扑精确性,引入液态时间常数(LTC)精修模块,将边界演化建模为由微分方程(ODE)控制的动态系统,通过连续时间步迭代优化掩码。在MICCAI FUSeg数据集上的全面评估表明,LSS-LTCNet达到最优边界对齐效果,取得86.96%的峰值Dice分数与8.91像素的95百分位豪斯多夫距离(HD95)。模型仅需2570万参数,显著优于更重的U-Net与变压器基线,在效率上表现优异。通过提供内在可视化审计轨迹与高保真预测,LSS-LTCNet为移动医疗(mHealth)环境下的计算机辅助诊断提供了鲁棒且透明的解决方案。
原文摘要 · Abstract (English)
Accurate semantic segmentation of foot ulcers is essential for automated wound monitoring, yet boundary delineation remains challenging due to tissue heterogeneity and poor contrast with surrounding skin. To overcome the limitations of standard intensity-based networks, we present LSS-LTCNet:an ante-hoc explainable framework synergizing deterministic structural priors with continuous-time neural dynamics. Our architecture departs from traditional black-box models by employing a Local Self-Similarity (LSS) mechanism that extracts dense, illumination-invariant texture descriptors to explicitly disentangle necrotic tissue from background artifacts. To enforce topological precision, we introduce a Liquid Time-Constant (LTC) refinement module that treats boundary evolution as an ODEgoverned dynamic system, iteratively refining masks over continuous time-steps. Comprehensive evaluation on the MICCAI FUSeg dataset demonstrates that LSS-LTCNet achieves state-of-the-art boundary alignment, securing a peak Dice score of 86.96% and an exceptional 95th percentile Hausdorff Distance (HD95) of 8.91 pixels. Requiring merely 25.70M parameters, the model significantly outperforms heavier U-Net and transformer baselines in efficiency. By providing inherent visual audit trails alongside high-fidelity predictions, LSS-LTCNet offers a robust and transparent solution for computer-aided diagnosis in mobile healthcare (mHealth) settings.
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