提出科学图像质量评估新框架，兼顾内容正确性与认知清晰度。

Scientific images fundamentally differ from natural and AI-generated images in that they encode structured domain knowledge rather than merely depict visual scenes. Assessing their quality therefore requires evaluating not only perceptual fidelity but also scientific correctness and logical completeness. However, existing image quality assessment (IQA) paradigms primarily focus on perceptual distortions or image-text alignment, implicitly assuming that depicted content is factually valid. This assumption breaks down in scientific contexts, where visually plausible figures may still contain conceptual errors or incomplete reasoning. To address this gap, we introduce Scientific Image Quality Assessment (SIQA), a framework that models scientific image quality along two complementary dimensions: Knowledge (Scientific Validity and Scientific Completeness) and Perception (Cognitive Clarity and Disciplinary Conformity). To operationalize this formulation, we design two evaluation protocols: SIQA-U (Understanding), which measures semantic comprehension of scientific content through multiple-choice tasks, and SIQA-S (Scoring), which evaluates alignment with expert quality judgments. We further construct the SIQA Challenge, consisting of an expert-annotated benchmark and a large-scale training set. Experiments across representative multimodal large language models (MLLMs) reveal a consistent discrepancy between scoring alignment and scientific understanding. While models can achieve strong agreement with expert ratings under SIQA-S, their performance on SIQA-U remains substantially lower. Fine-tuning improves both metrics, yet gains in scoring consistently outpace improvements in understanding. These results suggest that rating consistency alone may not reliably reflect scientific comprehension, underscoring the necessity of multidimensional evaluation for scientific image quality assessment.